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1. WO2020222014 - CALIBRATION OF A GAS SENSOR

Publication Number WO/2020/222014
Publication Date 05.11.2020
International Application No. PCT/GB2020/051066
International Filing Date 01.05.2020
IPC
A61B 5/1459 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH-value
1455using optical sensors, e.g. spectral photometrical oximeters
1459invasive, e.g. introduced into the body by a catheter
G01N 21/64 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
G01N 21/77 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
77by observing the effect on a chemical indicator
G01N 31/22 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
31Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroups; Apparatus specially adapted for such methods
22using chemical indicators
CPC
A61B 5/14552
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
1455using optical sensors, e.g. spectral photometrical oximeters
14551for measuring blood gases
14552Details of sensors specially adapted therefor
A61B 5/1495
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
1495Calibrating or testing of in-vivo probes
G01N 1/22
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
1Sampling; Preparing specimens for investigation
02Devices for withdrawing samples
22in the gaseous state
G01N 2021/6432
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
63optically excited
64Fluorescence; Phosphorescence
6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
6432Quenching
G01N 2021/772
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
77by observing the effect on a chemical indicator
7703using reagent-clad optical fibres or optical waveguides
7706Reagent provision
772Tip coated light guide
G01N 2021/7786
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
77by observing the effect on a chemical indicator
7769Measurement method of reaction-produced change in sensor
7786Fluorescence
Applicants
  • SCILOGICA CORP. [US]/[US]
  • SCILOGICA LTD. [GB]/[GB] (ST)
Inventors
  • BARWELL, Nicholas Paul
  • CRANE, Barry Colin
  • SAGAR, Praveen
  • MACKENZIE, Alasdair Allan
Agents
  • J A KEMP LLP
Priority Data
16/402,04002.05.2019US
19190352.506.08.2019EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CALIBRATION OF A GAS SENSOR
(FR) ÉTALONNAGE D'UN CAPTEUR DE GAZ
Abstract
(EN)
There is disclosed a method of calibrating a gas sensor comprising a luminescent compound having a luminescence lifetime that is quenched by a gaseous substance which uses a model of the relationship between the luminescence lifetime and the concentration of the gaseous substance that is modified by a calibration factor representing a proportion of the compound not being exposed to the gaseous substance, the method comprising: measuring values of the luminescence lifetime of the luminescent compound while the gas sensor is exposed to at least two known concentrations of the gaseous substance; and deriving the calibration factor from the measured values of the luminescence lifetime using the model. Also disclosed are a corresponding gas sensor apparatus for measuring the concentration of a gaseous substance in an environment, and method of measuring a concentration of a gaseous substance in an environment using a gas sensor.
(FR)
L'invention concerne un procédé d'étalonnage d'un capteur de gaz comprenant un composé luminescent ayant une durée de vie de luminescence qui est éteinte par une substance gazeuse qui utilise un modèle de la relation entre la durée de vie de luminescence et la concentration de la substance gazeuse qui est modifiée par un facteur d'étalonnage représentant une proportion du composé n'est pas exposée à la substance gazeuse, le procédé consistant à : mesurer des valeurs de la durée de vie de luminescence du composé luminescent pendant que le capteur de gaz est exposé à au moins deux concentrations connues de la substance gazeuse ; et dériver le facteur d'étalonnage à partir des valeurs mesurées de la durée de vie de luminescence à l'aide du modèle. L'invention concerne également un appareil de type capteur de gaz correspondant pour mesurer la concentration d'une substance gazeuse dans un environnement, et un procédé de mesure d'une concentration d'une substance gazeuse dans un environnement à l'aide d'un capteur de gaz.
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