Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020222007 - CHIMERIC PROTEIN COMPRISING A CASPASE 1 DOMAIN


Disclaimer The image version (PDF) available on PATENTSCOPE is the official version. This online html version is provided to assist users. Despite the great care taken in its compilation to ensure a precise and accurate representation of the data appearing on the printed document/images, errors and/or omissions cannot be excluded due to the data transmittal, conversion and inherent limitations of the (optional) machine translation processes used. Hyperlinks followed by this symbol , are to external resources that are not controlled by WIPO. WIPO disclaims all liability regarding the above points.

INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/GB2020/051056 P117641PCT
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
30 April 2020 01 May 2019
Applicant
AUTOLUS LIMITED
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
CHIMERIC PROTEIN COMPRISING A CASPASE 1 DOMAIN

5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     A61K 38/17 (2006.01)i; C12N 9/64 (2006.01)i; A61K 38/48 (2006.01)i; A61K 48/00 (2006.01)i; C07K 14/54 (2006.01)i; C07K 14/705 (2006.01)i; C07K 14/725 (2006.01)i; C12N 15/62 (2006.01)i; C12N 5/078 (2010.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     A61K; C12N; C07K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, BIOSIS

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
WO 2016135470 A1 (UCL BUSINESS PLC [GB]; SYNCONA PARTNERS LLP [GB]) 01 September 2016 (2016-09-01)
14
cited in the application
Y
Whole document, especially the claims
2-13,15-22
(2)
X
FAN LIANGFEN ET AL, "Improved artificial death switches based on caspases and FADD", HUMAN GENE THERAPY,,Vol. 10, No. 14, 20 September 1999 (1999-09-20), page 2273-2285,
XP002179899
1
Y
the whole document
2-13,15-22
(3)
X
WO 9950425 A2 (BAYLOR COLLEGE MEDICINE) 07 October 1999 (1999-10-07)
1
Y
the whole document
2-13,15-22
(4)
X
US 2004040047 A1 (SPENCER DAVID M [US] ET AL) 26 February 2004 (2004-02-26)
1
Y
Whole document, especially the claims
2-13,15-22
(5)
A
M. RENATUS ET AL, "Dimer formation drives the activation of the cell death protease caspase 9", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES,Vol. 98, No. 25, 04 December 2001 (2001-12-04), page 14250-14255,
XP055654313
1-22
the whole document
(6)
A
R. A. MACCORKLE ET AL, "Synthetic activation of caspases: Artificial death switches", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES,Vol. 95, No. 7, 31 March 1998 (1998-03-31), page 3655-3660,
XP055545497
1-22
the whole document
(7)
A
MARIN V ET AL, "Comparison of different suicide-gene strategies for the safety improvement of genetically manipulated T cells", HUMAN GENE THERAPY METHODS,,Vol. 23, No. 6, 01 January 2012 (2012-01-01), page 376-386,
XP009171601
1-22
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2016135470 A1
01 September 2016
AU 2016225190 A1
BR 112017013689 A2
CA 2973107 A1
CL 2017002134 A1
CN 107207621 A
EP 3197453 A1
JP 2018506975 A
JP 2020078359 A
KR 20170117555 A
RU 2017132293 A
SG 11201705300V A
US 2017354682 A1
US 2019015451 A1
WO 2016135470 A1
ZA 201704231 B
27 July 2017
06 March 2018
01 September 2016
16 March 2018
26 September 2017
02 August 2017
15 March 2018
28 May 2020
23 October 2017
25 March 2019
28 July 2017
14 December 2017
17 January 2019
01 September 2016
26 September 2018
WO 9950425 A2
07 October 1999
AU 3454799 A
WO 9950425 A2
18 October 1999
07 October 1999
US 2004040047 A1
26 February 2004
NONE
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
06 July 2020
Date of mailing of the international search report:
14 July 2020
Authorized officer:
Kools, Patrick
Top    Part 1: 1 2 3 4 5 6         Part 2: A B C D E