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1. WO2020221914 - PROCESS FOR THE PRODUCTION OF ETHYL 3-AMINO-1-[(3R,4S)-4-CYANOTETRAHYDROPYRAN-3-YL]PYRAZOLE-4-CARBOXYLATE THROUGH CHIRAL SEPARATION OF A RACEMIC MIXTURE

Publication Number WO/2020/221914
Publication Date 05.11.2020
International Application No. PCT/EP2020/062180
International Filing Date 01.05.2020
IPC
C07D 405/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
CPC
C07D 405/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
405Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
02containing two hetero rings
04directly linked by a ring-member-to-ring-member bond
Applicants
  • INTERVET INTERNATIONAL B.V. [NL]/[NL] (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JO, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, ZA, ZM, ZW)
  • INTERVET INC. [US]/[US] (US)
Inventors
  • CHASSAING, Christophe, Pierre, Alain
  • GRIMM, Karl-Heinz
Agents
  • INTERVET INTERNATIONAL BV
Priority Data
19172248.702.05.2019EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) PROCESS FOR THE PRODUCTION OF ETHYL 3-AMINO-1-[(3R,4S)-4-CYANOTETRAHYDROPYRAN-3-YL]PYRAZOLE-4-CARBOXYLATE THROUGH CHIRAL SEPARATION OF A RACEMIC MIXTURE
(FR) PROCÉDÉ DE PRODUCTION DE 3-AMINO-1-[(3R,4S)-4-CYANOTÉTRAHYDROPYRAN-3-YL] PYRAZOLE-4-CARBOXYLATE D'ÉTHYLE PAR SÉPARATION CHIRALE D'UN MÉLANGE RACÉMIQUE
Abstract
(EN)
A process for chiral separation of ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate (VI) from the racemic mixture of ethyl 3-amino-1-[(3R,4S)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate and ethyl 3-amino-1-[(3S,4R)-4-cyanotetrahydropyran-3-yl]pyrazole-4-carboxylate (V).
(FR)
Un procédé de séparation chirale de 3-amino-1-[(3R,4S)-4-cyanotétrahydropyran-3-yl] pyrazole-4-carboxylate d'éthyle (VI) à partir du mélange racémique de 3-amino-1-[(3R,4S)-4-cyanotétrahydropyran-3-yl] pyrazole-4-carboxylate d'éthyl et de 3-amino-1-[(3S,4R)-4-cyanotétrahydropyran-3-yl] pyrazole-4-carboxylate d'éthyle (V).
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