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1. WO2020221904 - MEASURING TIME TO FUSION AS A MEANS OF DETERMINING DEGREE OF PARALLEL ACTIVATION OF THE HEART

Publication Number WO/2020/221904
Publication Date 05.11.2020
International Application No. PCT/EP2020/062152
International Filing Date 30.04.2020
IPC
A61B 5/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
04Measuring bioelectric signals of the body or parts thereof
A61B 5/0402 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
04Measuring bioelectric signals of the body or parts thereof
0402Electrocardiography, i.e. ECG
A61B 5/0452 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
04Measuring bioelectric signals of the body or parts thereof
0402Electrocardiography, i.e. ECG
0452Detecting specific parameters of the electrocardiograph cycle
A61N 1/362 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
362Heart stimulators
A61N 1/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
CPC
A61B 2034/105
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
34Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
10Computer-aided planning, simulation or modelling of surgical operations
101Computer-aided simulation of surgical operations
105Modelling of the patient, e.g. for ligaments or bones
A61B 5/04011
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
04Measuring bioelectric signals of the body or parts thereof
04011Vector-cardiography
A61B 5/04012
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
04Measuring bioelectric signals of the body or parts thereof
04012Analysis of electro-cardiograms, electro-encephalograms, electro-myograms
A61B 5/04021
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
04Measuring bioelectric signals of the body or parts thereof
0402Electrocardiography, i.e. ECG
04021ECG simulator circuits
A61B 5/04028
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
04Measuring bioelectric signals of the body or parts thereof
0402Electrocardiography, i.e. ECG
04028Generation of artificial ECG signals based on measured signals, e.g. to compensate for missing leads
A61B 5/0452
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
04Measuring bioelectric signals of the body or parts thereof
0402Electrocardiography, i.e. ECG
0452Detecting specific parameters of the electrocardiograph cycle
Applicants
  • PACERTOOL AS [NO]/[NO]
Inventors
  • ODLAND, Hans Henrik
Agents
  • DEHNS
Priority Data
1906054.030.04.2019GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MEASURING TIME TO FUSION AS A MEANS OF DETERMINING DEGREE OF PARALLEL ACTIVATION OF THE HEART
(FR) MESURE DU TEMPS DE FUSION COMME MOYEN DE DÉTERMINATION DU DEGRÉ D'ACTIVATION PARALLÈLE DU CŒUR
Abstract
(EN)
A method for determining the degree of parallel activation of a heart undergoing pacing is disclosed. The method comprises calculating vectorcardiogram (VCG) or electrocardiogram (ECG) or electrogram (EGM) waveforms from right ventricular pacing (RVp) and left ventricular pacing (LVp). A synthetic biventricular pacing (BIVP) waveform is then generated by summing the VCG of the RVp and the LVp, or by summing the ECG of the RVp and the LVp, or by summing the EGM of the RVp and the LVp; and a corresponding EGM or ECG or VCG waveform from real BIVP is calculated. The method further comprises comparing the synthetic BIVP waveform and the real BIVP waveform; and calculating time to fusion by determining the point in time in which the activation from RVp and LVp meets and the synthetic and the real BIVP curves start to deviate. A delay in time to fusion indicates that a larger amount of tissue is activated before wave fronts for electrical activation meet, thereby indicating a higher degree of parallel activation.
(FR)
L'invention concerne un procédé permettant de déterminer le degré d'activation parallèle d'un cœur subissant une stimulation cardiaque. Le procédé comprend le calcul de formes d'onde de vectocardiogramme (VCG) ou d'électrocardiogramme (ECG) ou d'électrogramme (EGM) à partir de stimulation ventriculaire droite (RVp) et de stimulation ventriculaire gauche (LVp). Une forme d'onde de stimulation biventriculaire (BIVP) synthétique est ensuite générée par addition de VCG de RVp et de LVp, ou l'addition d'ECG de RVp et de LVp, ou par addition de l'EGM de RVp et de LVp; et une forme d'onde d'EGM ou d'ECG ou de VCG correspondante à partir de BIVP réel est calculée. Le procédé comprend en outre la comparaison de la forme d'onde de BIVP synthétique et de la forme d'onde de BIVP réelle; et le calcul du temps de fusion en déterminant le moment où l'activation à partir de RVp et de LVp se rencontrent et les courbes synthétique et réelle de BIVP commencent à s'écarter. Un retard dans le temps de fusion montre qu'une plus grande quantité de tissu est activée avant que des fronts d'onde pour une activation électrique se rencontrent, ce qui indique un degré plus élevé d'activation parallèle.
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