Feedback
Settings

Settings

Goto Application

1. WO2020221888 - CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR STABILIZING AGENTS

Submit observation
PermaLink
Disclaimer The image version (PDF) available on PATENTSCOPE is the official version. This online html version is provided to assist users. Despite the great care taken in its compilation to ensure a precise and accurate representation of the data appearing on the printed document/images, errors and/or omissions cannot be excluded due to the data transmittal, conversion and inherent limitations of the (optional) machine translation processes used. Hyperlinks followed by this symbol , are to external resources that are not controlled by WIPO. WIPO disclaims all liability regarding the above points.
INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
PATENT COOPERATION TREATY
PCT
INTERNATIONAL SEARCH REPORT
( PCT Article 18 and Rules 43 and 44)
International application No. Applicant's or agent's file reference
PCT/EP2020/062097 JaSt/CFTR/658
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
30 April 2020 30 April 2019
Applicant
VIB VZW
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
PART 1
PCT/EP2020/062097
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.
PART 2
PCT/EP2020/062097

A. CLASSIFICATION OF SUBJECT MATTER

     A61P 11/00 (2006.01)i; C07K 16/18 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     A61P; C07K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, BIOSIS, EMBASE

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
LIHUA HE ET AL, "Restoration of NBD1 Thermal Stability Is Necessary and Sufficient to Correct [increment]F508 CFTR Folding and Assembly", JOURNAL OF MOLECULAR BIOLOGY,Vol. 427, No. 1, 01 January 2015 (2015-01-01), page 106-120,
XP055668503
1,2,5-12
abstract
page 106, right-hand column, paragraph 1
page 111, right-hand column, paragraph 2
figures 3a, 3b
page 116, left-hand column, paragraph 4 - right-hand column, paragraph 1
page 117, left-hand column, paragraph 2
(2)
A
CALLEBAUT ISABELLE ET AL, "The implications of CFTR structural studies for cystic fibrosis drug development", CURRENT OPINION IN PHARMACOLOGY, ELSEVIER SCIENCE PUBLISHERS, NL,Vol. 34, 05 November 2017 (2017-11-05), page 112-118,
XP085291003
1-17
page 115, left-hand column, paragraph 1
page 114, right-hand column, paragraph 1
page 116, left-hand column, paragraph 2 - right-hand column
(3)
A
HUDSON RHEA P ET AL, "Conformational Changes Relevant to Channel Activity and Folding within the first Nucleotide Binding Domain of the Cystic Fibrosis Transmembrane Conductance Regulator", JOURNAL OF BIOLOGICAL CHEMISTRY,Vol. 287, No. 34, 17 August 2012 (2012-08-17), page 28480-28494,
XP055668670
1-17
page 28481, right-hand column, paragraph 1
page 28488, right-hand column, paragraph 2 - page 28489, right-hand column, paragraph 1
(4)
X,P
MAUD SIGOILLOT ET AL, "Domain-interface dynamics of CFTR revealed by stabilizing nanobodies", NATURE COMMUNICATIONS,Vol. 10, No. 1, 14 June 2019 (2019-06-14),
XP055668506
3,5-8,10-13,15-17
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
24 July 2020
Date of mailing of the international search report:
07 August 2020
Authorized officer:
Irion, Andrea
Top    Part 1: 1 2 3 4 5 6         Part 2: A B C D E  â–²

# -