Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020221038 - BENZOTHIOPHENE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF

Publication Number WO/2020/221038
Publication Date 05.11.2020
International Application No. PCT/CN2020/085525
International Filing Date 20.04.2020
IPC
C07D 333/64 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
333Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
50condensed with carbocyclic rings or ring systems
52Benzo thiophenes; Hydrogenated benzo thiophenes
62with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
64Oxygen atoms
C07D 409/14 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
409Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
14containing three or more hetero rings
A61K 31/381 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
38having sulfur as a ring hetero atom
381having five-membered rings
A61K 31/4155 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
4151,2-Diazoles
4155not condensed and containing further heterocyclic rings
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • 四川科伦博泰生物医药股份有限公司 SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. [CN]/[CN]
Inventors
  • 刘金明 LIU, Jinming
  • 任云 REN, Yun
  • 田强 TIAN, Qiang
  • 宋宏梅 SONG, Hongmei
  • 薛彤彤 XUE, Tongtong
  • 王晶翼 WANG, Jingyi
Agents
  • 北京永新同创知识产权代理有限公司 NTD UNIVATION INTELLECTUAL PROPERTY AGENCY LTD.
Priority Data
201910359616.030.04.2019CN
Publication Language Chinese (ZH)
Filing Language Chinese (ZH)
Designated States
Title
(EN) BENZOTHIOPHENE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF
(FR) COMPOSÉ DE BENZOTHIOPHÈNE, SON PROCÉDÉ DE PRÉPARATION ET SON UTILISATION
(ZH) 苯并噻吩类化合物及其制备方法和用途
Abstract
(EN)
A compound represented by formula (I) or a pharmaceutically acceptable salt, a stereoisomer, a tautomer, a polymorph, a solvate, an N-oxide, an isotope labeled compound, a metabolite or a prodrug thereof, a pharmaceutical composition and a pill container comprising same, a preparation method therefor, and the use thereof in the preparation of drugs for preventing or treating STING-mediated related diseases. (I)
(FR)
L'invention concerne un composé représenté par la formule (I) ou un sel pharmaceutiquement acceptable, un stéréoisomère, un tautomère, un polymorphe, un solvate, un N-oxyde, un composé marqué par un isotope, un métabolite ou un promédicament de celui-ci, une composition pharmaceutique et un pilulier la contenant, un procédé de préparation associé, et leur utilisation dans la préparation de médicaments pour la prévention ou le traitement de maladies associées à médiation par STING. (I)
(ZH)
一种式I的化合物或其药学上可接受的盐、立体异构体、互变异构体、多晶型物、溶剂合物、N-氧化物、同位素标记的化合物、代谢物或前药,包含其的药物组合物和药盒,其制备方法及其在制备用于预防或治疗STING介导的相关疾病的药物中的用途。
Latest bibliographic data on file with the International Bureau