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1. WO2020205560 - SULFONYLAMIDE COMPOUNDS AS CDK2 INHIBITORS


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/US2020/025335 20443-0604WO1
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
27 March 2020 29 March 2019
Applicant
INCYTE CORPORATION
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
1. With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
a. forming part of the international application as filed:
in the form of an Annex C/ST.25 text file.
on paper or in the form of an image file.
b. furnished together with the international application under PCT Rule 13ter.1(a) for the purposes of international search only in the form of an Annex C/ST.25 text file.
c. furnished subsequent to the international filing date for the purposes of international search only:
in the form of an Annex C/ST.25 text file (Rule 13ter.1(a)).
on paper or in the form of an image file (Rule 13ter.1(b) and Administrative Instructions, Section 713).
2.
In addition, in the case that more than one version or copy of a sequence listing has been filed or furnished, the required statements that the information in the subsequent or additional copies is identical to that forming part of the application as filed or does not go beyond the application as filed, as appropriate, were furnished.
3.
Additional comments:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.

The present application provides sulfonyl amide compounds of formula (I), which are inhibitors of cyclin-dependent kinase 2 (CDK2), as well as pharmaceutical compositions thereof, and methods of treating cancer using the same.


6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     A61P 35/00 (2006.01)i; C07D 487/04 (2006.01)i; A61K 31/519 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     A61P; C07D; A61K
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, CHEM ABS Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
WO 2007140222 A2 (NOVARTIS AG [CH]; NOVARTIS PHARMA GMBH [AT] ET AL.) 06 December 2007 (2007-12-06)
1-35
claims 1-43
page 3, lines 24-26
(2)
A
VERONIKA MALÍNKOVÁ ET AL, "Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014)", EXPERT OPINION ON THERAPEUTIC PATENTS,Vol. 25, No. 9, 10 July 2015 (2015-07-10), page 953-970,
XP055699454
1-35
page 955; figure 1
page 956; table 1
page 957, paragraph 2.4 - page 959
page 961, paragraph 2.8 - page 963
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2007140222 A2
06 December 2007
AR 061124 A1
AR 108179 A2
AU 2007267645 A1
BR PI0712816 A2
CA 2652044 A1
CL 2007001504 A1
CN 101594871 A
CR 10433 A
CU 20080223 A7
EA 200802332 A1
EC SP088910 A
EP 2029145 A2
ES 2623133 T3
GE P20115283 B
GT 200800258 A
HN 2008001752 A
HR P20170631 T1
IL 195086 A
JO 3235 B1
JP 5740417 B2
JP 2009538341 A
JP 2013091665 A
KR 20090014219 A
MA 30557 B1
ME 00486 B
MY 150650 A
NO 343182 B1
NZ 572549 A
PE 20080263 A1
PL 2029145 T3
PT 2029145 T
SG 172632 A1
SM AP200800069 A
TN SN08481 A1
TW 200815011 A
UA 95632 C2
US 2009318441 A1
US 2012207763 A1
UY 30369 A1
WO 2007140222 A2
ZA 200809382 B
06 August 2008
25 July 2018
06 December 2007
23 October 2012
06 December 2007
09 May 2008
02 December 2009
15 January 2009
20 July 2010
30 June 2009
30 December 2008
04 March 2009
10 July 2017
12 September 2011
24 June 2009
12 July 2011
11 August 2017
29 October 2015
08 March 2018
24 June 2015
05 November 2009
16 May 2013
06 February 2009
01 July 2009
10 October 2011
14 February 2014
26 November 2018
28 October 2011
12 May 2008
31 August 2017
24 April 2017
28 July 2011
23 December 2008
14 April 2010
01 April 2008
25 August 2011
24 December 2009
16 August 2012
02 January 2008
06 December 2007
30 December 2009
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
28 May 2020
Date of mailing of the international search report:
16 June 2020
Authorized officer:
Marzi, Elena
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