Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020205234 - CIRCUITRY TO ASSIST WITH NEURAL SENSING IN AN IMPLANTABLE STIMULATOR DEVICE IN THE PRESENCE OF STIMULATION ARTIFACTS

Publication Number WO/2020/205234
Publication Date 08.10.2020
International Application No. PCT/US2020/023182
International Filing Date 17.03.2020
IPC
A61N 1/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
A61N 1/05 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
02Details
04Electrodes
05for implantation or insertion into the body, e.g. heart electrode
A61N 1/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
1Electrotherapy; Circuits therefor
18Applying electric currents by contact electrodes
32alternating or intermittent currents
36for stimulation, e.g. heart pace-makers
A61B 5/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
CPC
A61B 2562/0209
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2562Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
02Details of sensors specially adapted for in-vivo measurements
0209Special features of electrodes classified in A61B5/04001, A61B5/0408, A61B5/042, A61B5/0478, A61B5/0492 or A61B5/053
A61B 5/04001
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
04Measuring bioelectric signals of the body or parts thereof
04001adapted to neuroelectric signals, e.g. nerve impulses
A61B 5/4848
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
48Other medical applications
4848Monitoring or testing the effects of treatment, e.g. of medication
A61B 5/686
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
6846specially adapted to be brought in contact with an internal body part, i.e. invasive
6847mounted on an invasive device
686Permanently implanted devices, e.g. pacemakers, other stimulators, biochips
A61B 5/7217
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
72Signal processing specially adapted for physiological signals or for diagnostic purposes
7203for noise prevention, reduction or removal
7217of noise originating from a therapeutic or surgical apparatus, e.g. from a pacemaker
A61B 5/7225
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
72Signal processing specially adapted for physiological signals or for diagnostic purposes
7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
Applicants
  • BOSTON SCIENTIFIC NEUROMODULATION CORPORATION [US]/[US]
Inventors
  • WEERAKOON, Pujitha
  • MARNFELDT, Goran N.
Agents
  • LEWIS, Terril
Priority Data
62/825,98129.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CIRCUITRY TO ASSIST WITH NEURAL SENSING IN AN IMPLANTABLE STIMULATOR DEVICE IN THE PRESENCE OF STIMULATION ARTIFACTS
(FR) CIRCUIT POUR AIDER À LA DÉTECTION NEURONALE DANS UN DISPOSITIF DE STIMULATEUR POUVANT ÊTRE IMPLANTÉ EN PRÉSENCE D'ARTEFACTS DE STIMULATION
Abstract
(EN)
Sense amplifier circuits particularly useful in sensing neural responses in an Implantable Pulse Generator (IPG) are disclosed. The IPG includes a plurality of electrodes, with one selected as a sensing electrode and another selected as a reference to differentially sense the neural response in a manner that subtracts a common mode voltage (e.g., stimulation artifact) from the measurement. The circuits include a differential amplifier which receives the selected electrodes at its inputs, and comparator circuitries to assess each differential amplifier input to determine whether it is of a magnitude that is consistent with the differential amplifier's input requirements. Based on these determinations, an enable signal is generated which informs whether the output of the differential amplifier validly provides the neural response at any point in time. Further, clamping circuits are connected to the differential amplifier inputs to clamp these inputs in magnitude to prevent the differential amplifier from damage.
(FR)
L'invention concerne des circuits amplificateurs de détection particulièrement utiles dans la détection de réponses neuronales dans un générateur d'impulsions pouvant être implanté (IPG). L'IPG comprend une pluralité d'électrodes, l'une étant sélectionnée en tant qu'électrode de détection et une autre étant sélectionnée en tant que référence pour détecter de manière différentielle la réponse neuronale d'une manière qui soustrait de la mesure une tension de mode commun (par exemple, un artefact de stimulation). Les circuits comprennent un amplificateur différentiel qui reçoit les électrodes sélectionnées à ses entrées, et des circuits de comparateur pour évaluer chaque entrée d'amplificateur différentiel afin de déterminer s'il s'agit d'une amplitude qui est cohérente avec les exigences d'entrée de l'amplificateur différentiel. Sur la base de ces déterminations, un signal d'activation est généré, celui-ci informant de la possibilité que la sortie de l'amplificateur différentiel fournit de manière valide la réponse neuronale à n'importe quel moment dans le temps. En outre, des circuits de serrage sont connectés aux entrées d'amplificateur différentiel pour serrer ces entrées en amplitude afin d'empêcher l'endommagement de l'amplificateur différentiel.
Latest bibliographic data on file with the International Bureau