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1. WO2020204640 - NOVEL CONTRAST AGENT COMPOSITION COMPRISING METABOLITE AS EFFECTIVE COMPONENT

Publication Number WO/2020/204640
Publication Date 08.10.2020
International Application No. PCT/KR2020/004532
International Filing Date 02.04.2020
IPC
A61K 49/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
06Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
08characterised by the carrier
10Organic compounds
Applicants
  • 연세대학교 산학협력단 INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITY [KR]/[KR]
Inventors
  • 주찬규 JOO, Chan Gyu
  • 허용민 HUH, Yong Min
  • 손혜영 SON, Hye Young
Agents
  • 특허법인 충현 CHUNG HYUN PATENT & LAW FIRM
Priority Data
10-2019-003988805.04.2019KR
10-2020-004051102.04.2020KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) NOVEL CONTRAST AGENT COMPOSITION COMPRISING METABOLITE AS EFFECTIVE COMPONENT
(FR) NOUVELLE COMPOSITION D'AGENT DE CONTRASTE COMPRENANT UN MÉTABOLITE EN TANT QUE PRINCIPE ACTIF
(KO) 대사체를 유효성분으로 포함하는 신규한 조영제 조성물
Abstract
(EN)
The present invention relates to a contrast agent composition for magnetic resonance imaging (MRI), and more specifically, a composition for T2 exchange (T2ex) magnetic resonance imaging. The present invention can provide diagnostic information for various diseases involving metabolic abnormalities, specifically glutamine metabolic abnormalities, and inflammatory diseases. The present invention has the same level of image resolution as a conventional MRI image while showing metabolic processes in real time, and thus can be usefully utilized for highly reliable non-invasive diagnosis.
(FR)
La présente invention concerne une composition d'agent de contraste destinée à l'imagerie par résonance magnétique (IRM), et plus particulièrement, une composition destinée à l'imagerie par résonance magnétique d'échange T2 (T2ex). La présente invention peut fournir des informations diagnostiques pour diverses maladies impliquant des anomalies métaboliques, en particulier des anomalies métaboliques de la glutamine, et des maladies inflammatoires. La présente invention offre le même niveau de résolution d'image qu'une image d'IRM classique tout en montrant les processus métaboliques en temps réel, et peut donc être utilisée utilement pour un diagnostic non invasif hautement fiable.
(KO)
본 발명은 자기공명영상(MRI)용 조영제 조성물, 보다 구체적으로는 T2 교환 (T2ex) 자기공명영상용 조성물에 관한 것이다. 본 발명은 대사 이상, 구체적으로는 글루타민 대사 이상을 수반하는 다양한 질환 및 염증성 질환에 대한 진단적 정보를 제공할 수 있다. 본 발명은 대사과정을 실시간으로 보여주면서도 종래의 MRI 영상과 동일한 수준의 이미지 해상도를 가져 신뢰도 높은 비침습적 진단에 유용하게 이용될 수 있다.
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