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1. WO2020201525 - MULTIFUNCTIONAL COMPOUNDS FOR POLYMER MATRIX GRAFTING

Publication Number WO/2020/201525
Publication Date 08.10.2020
International Application No. PCT/EP2020/059604
International Filing Date 03.04.2020
IPC
G01N 33/58 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
C12Q 1/6841 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6813Hybridisation assays
6841In situ hybridisation
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
CPC
C12Q 1/6841
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6813Hybridisation assays
6841In situ hybridisation
G01N 33/582
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
58involving labelled substances
582with fluorescent label
G01N 33/6803
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
6803General methods of protein analysis not limited to specific proteins or families of proteins
Applicants
  • KATHOLIEKE UNIVERSITEIT LEUVEN [BE]/[BE]
Inventors
  • HOFKENS, Johan
  • WEN, Gang
  • LEEN, Volker
Priority Data
1904834.705.04.2019GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTIFUNCTIONAL COMPOUNDS FOR POLYMER MATRIX GRAFTING
(FR) COMPOSÉS MULTIFONCTIONNELS DE GREFFAGE DE MATRICE POLYMÈRE
Abstract
(EN)
The invention relates to methods for identifying and locating a biomolecule in a sample, using a multifunctional reagent with moieties, R1, R2, R3 and Y wherein R1 is a specific ligand for a biological structure, R2 is a reactive group capable of binding covalently to a polymeric matrix, R3 is a reporter moiety, and Y is a moiety covalently connecting R1, R2 and R3.
(FR)
L'invention concerne des méthodes d'identification et de localisation d'une biomolécule dans un échantillon, à l'aide d'un réactif multifonctionnel comportant des fractions, R1, R2, R3 et Y, où R1 est un ligand spécifique pour une structure biologique, R2 est un groupe réactif pouvant se lier de manière covalente à une matrice polymère, R3 est une fraction rapporteur, et Y est une fraction liant de manière covalente R1, R2 et R3.
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