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1. WO2020198834 - TREATMENT OF MICROBIAL INFECTIONS USING SCPPPQ1 PROTEINS AND DERIVED PEPTIDES

Publication Number WO/2020/198834
Publication Date 08.10.2020
International Application No. PCT/CA2019/051839
International Filing Date 18.12.2019
IPC
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
A61K 38/17 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
A61L 2/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
2Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
16using chemical substances
A61P 1/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
02Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
A61P 31/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
A61P 31/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
10Antimycotics
Applicants
  • NANCI, Antonio [CA]/[CA]
  • MOFFATT, Pierre [CA]/[CA]
  • FOUILLEN, Aurélien [CA]/[CA]
  • MARY, Charline [CA]/[CA]
Inventors
  • NANCI, Antonio
  • MOFFATT, Pierre
  • FOUILLEN, Aurélien
  • MARY, Charline
Agents
  • LAVERY, DE BILLY, L.L.P.
Priority Data
62/829,73205.04.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TREATMENT OF MICROBIAL INFECTIONS USING SCPPPQ1 PROTEINS AND DERIVED PEPTIDES
(FR) TRAITEMENT D'INFECTIONS MICROBIENNES À L'AIDE DE PROTÉINES SCPPPQ1 ET DE PEPTIDES DÉRIVÉS
Abstract
(EN)
Polypeptides, peptides, peptidomimetics, and salts thereof derived from secretory calcium-binding phosphoprotein-proline glutamine-rich 1 (SCPPPQ1) are described. The use of these polypeptides, peptides, peptidomimetics, and salts thereof, and compositions comprising same, as antibacterial or antifungal agents is also described. Methods for treating bacterial or fungal infections and related diseases such as periodontal or gingival diseases, or for cleaning or disinfecting a surface, are also described.
(FR)
L'invention concerne des polypeptides, des peptides, des peptidomimétiques et des sels de ceux-ci dérivés de la phosphoprotéine-proline riche en glutamine sécrétoire liant le calcium 1 (SCPPPQ1). L'invention concerne également l'utilisation de ces polypeptides, peptides, peptidomimétiques et sels de ceux-ci, et des compositions les comprenant, en tant qu'agents antibactériens ou antifongiques. L'invention concerne en outre des méthodes de traitement d'infections bactériennes ou fongiques et de maladies associées telles que des maladies parodontales ou gingivales, ou pour le nettoyage ou la désinfection d'une surface.
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