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1. WO2020198705 - COMBINATIONS USEFUL IN A METHOD FOR TREATING SARCOMA

Publication Number WO/2020/198705
Publication Date 01.10.2020
International Application No. PCT/US2020/025532
International Filing Date 27.03.2020
IPC
C07D 471/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/-C07D463/251
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 403/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
04directly linked by a ring-member-to-ring- member bond
C07D 487/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • PTC THERAPEUTICS, INC. [US]/[US]
Inventors
  • WEETALL, Marla, L.
  • CAO, Liangxian
  • SHEEDY, Josephine
  • SPIEGEL, Robert
Agents
  • SCOLA, Jr., Daniel, A.
  • ABBRUZZESE, Salvatore, J.
  • SOPKO, John
  • NEUNER, Robert
  • WILKOVICH, Andrea, M.
Priority Data
62/825,01727.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) COMBINATIONS USEFUL IN A METHOD FOR TREATING SARCOMA
(FR) COMBINAISONS UTILES DANS UN PROCÉDÉ DE TRAITEMENT DU SARCOME
Abstract
(EN)
One aspect described herein includes a method for treating sarcoma in a subject in need thereof comprising, administering to the subject an effective amount of a small molecule compound. More particularly, another aspect described herein includes a method for treating sarcoma in a subject in need thereof comprising, administering to the subject an effective amount of the small molecule compound described herein in combination with a chemotherapeutic agent.
(FR)
Un aspect de l'invention concerne un procédé de traitement d'un sarcome chez un sujet en ayant besoin, comprenant l'administration au sujet d'une quantité efficace d'un composé à petites molécules. Plus particulièrement, un autre aspect de l'invention concerne un procédé de traitement d'un sarcome chez un sujet en ayant besoin, comprenant l'administration au sujet d'une quantité efficace du composé à petites molécules décrit ici en combinaison avec un agent chimiothérapeutique.
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