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1. WO2020198682 - METHODS FOR SYNTHESIZING β-HOMOAMINO ACIDS

Publication Number WO/2020/198682
Publication Date 01.10.2020
International Application No. PCT/US2020/025468
International Filing Date 27.03.2020
IPC
C07K 14/70546
C07K 14/47 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
46from vertebrates
47from mammals
Applicants
  • PROTAGONIST THERAPEUTICS, INC. [US]/[US]
Inventors
  • MANTHATI, Suresh Kumar
  • BHANDARI, Ashok
  • MASJEDIZADEH, Mohammad Reza
Agents
  • LAHERTY, Carol
  • TEAGUE, Lawrence
Priority Data
62/825,63528.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS FOR SYNTHESIZING β-HOMOAMINO ACIDS
(FR) PROCÉDÉS DE SYNTHÈSE DE β-HOMOAMINOACIDES
Abstract
(EN)
Methods of making β-homoamino acids as intermediate for synthesis of peptide monmer and dimer α4β7-antagonists are disclosed. The disclosed methods include solid phase and solution phase methods.
(FR)
L'invention concerne des procédés de préparation de β-homoaminoacides utilisés comme intermédiaire pour la synthèse d'antagonistes monomères et dimères peptidiques d'α4β7. Les procédés selon l'invention comprennent des procédés en phase solide et en phase de solution.
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