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1. WO2020198644 - MIXTURES OF SYNTHETIC COPOLYPEPTIDE HYDROGELS

Publication Number WO/2020/198644
Publication Date 01.10.2020
International Application No. PCT/US2020/025377
International Filing Date 27.03.2020
IPC
A61K 47/42 2017.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
C07K 2/00 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2Peptides of undefined number of amino acids; Derivatives thereof
C07K 17/04 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
17Carrier-bound or immobilised peptides; Preparation thereof
02Peptides being immobilised on, or in, an organic carrier
04entrapped within the carrier, e.g. gel, hollow fibre
C08J 3/00 2006.01
CCHEMISTRY; METALLURGY
08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
JWORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H142
3Processes of treating or compounding macromolecular substances
Applicants
  • THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US]/[US]
Inventors
  • DEMING, Timothy, J.
  • SUN, Yintao
Agents
  • HALSTEAD, David, P.
  • CAO, Yichen
  • AKHIEZER, Alexander
  • CAI, Mi
  • ABELLEIRA, Susan, M.
Priority Data
62/824,57127.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MIXTURES OF SYNTHETIC COPOLYPEPTIDE HYDROGELS
(FR) MÉLANGES D'HYDROGELS COPOLYPEPTIDIQUES SYNTHÉTIQUES
Abstract
(EN)
The present disclosure is directed to physical mixtures of diblock copolypeptide hydrogel (DCH) systems. These systems exhibit mechanical strength and stiffness that are synergistically increased over the individual component DCHs, to greater than would be expected for a linear combination of the components. Such systems may have utility in biomedical applications such as drug delivery.
(FR)
La présente invention concerne des mélanges physiques de systèmes d'hydrogel copolypeptidique dibloc (DCH). Ces systèmes présentent une résistance mécanique et une rigidité qui sont augmentées de manière synergique sur les composants individuels DCH, à un niveau supérieur à celui attendu pour une combinaison linéaire des composants. De tels systèmes peuvent avoir une utilité dans des applications biomédicales telles que l'administration de médicaments.
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