Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020198614 - LYOPHILIZED ANTIBODY PANEL

Publication Number WO/2020/198614
Publication Date 01.10.2020
International Application No. PCT/US2020/025296
International Filing Date 27.03.2020
IPC
A61K 9/19 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
14Particulate form, e.g. powders
19lyophilised
G01N 15/10 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
15Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
10Investigating individual particles
G01N 27/62 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
62by investigating the ionisation of gases; by investigating electric discharges, e.g. emission of cathode
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
G01N 33/53 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
G01N 33/532 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
531Production of immunochemical test materials
532Production of labelled immunochemicals
Applicants
  • FLUIDIGM CANADA INC. [CA]/[CA]
  • FLUIDIGM CORPORATION [US]/[US]
Inventors
  • LI, Stephen K.H.
  • MAJONIS, Daniel
  • BARANOV, Vladimir
  • ORNATSKY, Olga
  • ALLO, Bedilu
  • BANDURA, Dmitry
  • THOM, Colin
  • STELZER, Greg
  • LOBODA, Alexander
Agents
  • HSU, David D.
  • BERTELSON, Michael A.
  • KILPATRICK TOWNSEND & STOCKTON LLP
Priority Data
62/824,91727.03.2019US
62/951,54620.12.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LYOPHILIZED ANTIBODY PANEL
(FR) PANEL D'ANTICORPS LYOPHILISÉS
Abstract
(EN)
A lyophilized antibody panel is disclosed for interrogation using elemental analysis. The antibody panel includes multiple antibodies each element-tagged or element-labelled with one or more isotopes such that each different antibody is isotopically distinguishable from the other antibodies. Each element tag can include one or more unique isotopes or unique combinations of isotopes. The set of element-tagged antibodies can be lyophilized in admixture. Thus, the lyophilized element-tagged antibody panel can be easily and efficiently resuspended and mixed with a sample prior to interrogation with an elemental analyzer, such as a mass spectrometer. This lyophilized element-tagged antibody panel can provide the benefits of an element-tagged assay while also being easy to use and remaining stable for long durations.
(FR)
La présente invention concerne un panel d'anticorps lyophilisés pour une interrogation en utilisant l'analyse élémentaire. Le panel d'anticorps comprend de multiples anticorps, chaque anticorps étant étiqueté par un élément ou marqué par un élément avec un ou plusieurs isotopes de telle sorte que chaque anticorps différent peut être distingué par voie isotopique des autres anticorps. Chaque étiquette d'élément peut comprendre un ou plusieurs isotopes uniques ou des combinaisons uniques d'isotopes. L'ensemble d'anticorps étiquetés par un élément peut être lyophilisé en mélange. Ainsi, le panel d'anticorps lyophilisé étiqueté par un élément peut être facilement et efficacement remis en suspension et mélangé avec un échantillon avant l'interrogation avec un analyseur élémentaire, tel qu'un spectromètre de masse. Ce panel d'anticorps lyophilisé étiqueté par un élément peut fournir les avantages d'un dosage étiqueté par un élément tout en étant également facile à utiliser et restant stable pendant de longues durées.
Latest bibliographic data on file with the International Bureau