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1. WO2020198534 - IMAGING AGENTS AND METHODS OF USING THE SAME

Publication Number WO/2020/198534
Publication Date 01.10.2020
International Application No. PCT/US2020/025072
International Filing Date 26.03.2020
IPC
A61K 49/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
49Preparations for testing in vivo
06Nuclear magnetic resonance (NMR) contrast preparations; Magnetic resonance imaging (MRI) contrast preparations
CPC
A61B 6/481
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
6Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
48Diagnostic techniques
481involving the use of contrast agents
A61B 6/503
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
6Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
50Clinical applications
503involving diagnosis of heart
A61B 6/504
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
6Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
50Clinical applications
504involving diagnosis of blood vessels, e.g. by angiography
A61K 31/137
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
13Amines
135having aromatic rings ; , e.g. ketamine, nortriptyline
137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine ; or methadone
A61K 31/439
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
439the ring forming part of a bridged ring system, e.g. quinuclidine
A61K 47/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
08containing oxygen, ; e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
Applicants
  • SICREATIONS, LLC [US]/[US]
Inventors
  • ECHOLS, Michael, Scott
Agents
  • GREENFELD, Robert
  • LI, Z., Ying
  • FOX, Harrold, H.
  • CARACAPPA, John, M.
  • BICKHAM, Timothy, C.
Priority Data
16/831,68826.03.2020US
62/824,05126.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) IMAGING AGENTS AND METHODS OF USING THE SAME
(FR) AGENTS D'IMAGERIE ET PROCÉDÉS D'UTILISATION DE CEUX-CI
Abstract
(EN)
A composition for internal imaging of a subject includes an imaging contrast agent and one or more carrier agents that can pass through cellular and tissue membranes. Examples of imaging contrast agents are iodine-based, silver- based, or barium-based. Examples of carrier agents are dimethyl sulfoxide, urea, or an alcohol. Methods for internally imaging a subject using such a composition are also disclosed.
(FR)
L'invention concerne une composition d'imagerie interne d'un sujet qui comprend un agent de contraste d'imagerie et un ou plusieurs agents de support qui peuvent passer à travers des membranes cellulaires et tissulaires. Des exemples d'agents de contraste d'imagerie sont à base d'iode, à base d'argent ou à base de baryum. Des exemples d'agents de support sont le diméthylsulfoxyde, l'urée ou un alcool. L'invention concerne également des procédés d'imagerie interne d'un sujet à l'aide d'une telle composition.
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