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1. WO2020198530 - TUNABLE NANOPILLAR AND NANOGAP ELECTRODE STRUCTURES AND METHODS THEREOF

Publication Number WO/2020/198530
Publication Date 01.10.2020
International Application No. PCT/US2020/025068
International Filing Date 26.03.2020
IPC
G01N 27/327 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
327Biochemical electrodes
G01N 27/30 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
27Investigating or analysing materials by the use of electric, electro-chemical, or magnetic means
26by investigating electrochemical variables; by using electrolysis or electrophoresis
28Electrolytic cell components
30Electrodes, e.g. test electrodes; Half-cells
C12Q 1/6869 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6869Methods for sequencing
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C12Q 1/00 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
Applicants
  • ROSWELL BIOTECHNOLOGIES, INC. [US]/[US]
Inventors
  • JIN, Sungho
  • CHOI, Chulmin
  • MOLA, Paul
Agents
  • PAPPALARDO, Paul A.
Priority Data
62/824,23026.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TUNABLE NANOPILLAR AND NANOGAP ELECTRODE STRUCTURES AND METHODS THEREOF
(FR) STRUCTURES D'ÉLECTRODES À NANOPILIERS ET À NANOESPACES ACCORDABLES ET LEURS PROCÉDÉS
Abstract
(EN)
New methods in nanolithography provide nanoscale structures usable in molecular electronic sensors, such as for nucleotide sequencing. In various embodiments, tunable nanopillars are grown in holes nanopatterned in a resist layer over pairs of electrodes, with the resulting nanopillars acting as vertical extensions of the electrodes buried underneath the resist layer. Exposed top surfaces of the nanopillars are limited in size, thus providing controlled binding of a single or at most just a few bridge molecules between nanopillars in a pair of nanopillars.
(FR)
De nouveaux procédés en nanolithographie fournissent des structures à l'échelle nanométrique utilisables dans des capteurs électroniques moléculaires, par exemple pour le séquençage de nucléotides. Dans divers modes de réalisation, des nanopiliers accordables sont mis en croissance dans des trous nanostructurés dans une couche de réserve sur des paires d'électrodes, les nanopiliers ainsi obtenus agissant en tant qu'extensions verticales des électrodes enfouies sous la couche de réserve. Les surfaces supérieures exposées des nanopiliers sont limitées en taille, fournissant ainsi une liaison contrôlée d'une seule molécule de pontage ou au plus juste quelques molécules de pontage entre des nanopiliers dans une paire de nanopiliers.
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