Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020198469 - METHOD FOR TREATING EPIDERMAL GROWTH FACTOR RECEPTOR-DRIVEN CANCERS WITH PROTEIN KINASE C INHIBITORS IN COMBINATION WITH AN EGFR-TYROSINE KINASE INHIBITOR

Publication Number WO/2020/198469
Publication Date 01.10.2020
International Application No. PCT/US2020/024954
International Filing Date 26.03.2020
IPC
C07D 241/26 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
241Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
02not condensed with other rings
10having three double bonds between ring members or between ring members and non-ring members
14with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
26with nitrogen atoms directly attached to ring carbon atoms
A61K 31/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C12Q 1/6886 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
Applicants
  • IDEAYA BIOSCIENCES INC. [US]/[US]
Inventors
  • MOUNIR, Zineb
  • WAGLE, Marie-Claire
  • O'BRIEN, Carol
Agents
  • TRINQUE, Brian, C.
  • ANIS, Hissan
  • AREZINA, Vladimir, I.
  • BARTON, Steven, K.
  • CHEN, Xiaoyue, (Peter)
Priority Data
62/824,63827.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR TREATING EPIDERMAL GROWTH FACTOR RECEPTOR-DRIVEN CANCERS WITH PROTEIN KINASE C INHIBITORS IN COMBINATION WITH AN EGFR-TYROSINE KINASE INHIBITOR
(FR) MÉTHODE DE TRAITEMENT DE CANCERS ENTRAÎNÉS PAR LE RÉCEPTEUR DU FACTEUR DE CROISSANCE ÉPIDERMIQUE AVEC DES INHIBITEURS DE PROTÉINE KINASE C EN COMBINAISON AVEC UN INHIBITEUR DE TYROSINE KINASE EGFR
Abstract
(EN)
Provided are methods for treating epidermal growth factor receptor (EGFR)-driven cancers such as non-small cell lung cancer (NSCLC) by a protein kinase C (PKC) inhibitor in combination with an EGFR tyrosine kinase inhibitor.
(FR)
L'invention concerne des méthodes de traitement de cancers entraînés par le récepteur du facteur de croissance épidermique (EGFR) tels que le cancer du poumon non à petites cellules (NSCLC) par un inhibiteur de protéine kinase C (PKC) en combinaison avec un inhibiteur de tyrosine kinase EGFR.
Latest bibliographic data on file with the International Bureau