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1. WO2020198412 - MODULATION OF TRANSGENE EXPRESSION

Publication Number WO/2020/198412
Publication Date 01.10.2020
International Application No. PCT/US2020/024823
International Filing Date 26.03.2020
IPC
C12N 15/82 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
82for plant cells
C07K 14/325 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
195from bacteria
32from Bacillus (G)
325Bacillus thuringiensis crystal peptide (delta-endotoxin)
C12N 15/113 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A01N 37/44 2006.01
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
37Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
44containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio-analogue of a carboxylic group, e.g. amino-carboxylic acids
Applicants
  • SYNGENTA CROP PROTECTION AG [CH]/[CH]
  • SYNGENTA CROP PROTECTION [US]/[US] (US)
Inventors
  • GREEN, Julie Leonard
  • KELLIHER, Timothy Joseph
Agents
  • WARREN, Gregory
Priority Data
62/825,10728.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MODULATION OF TRANSGENE EXPRESSION
(FR) MODULATION D'EXPRESSION DE TRANSGÈNES
Abstract
(EN)
Compositions and methods of modulating, for example reducing, recombinant insecticidal protein expression in male reproductive cells and/or tissues of transgenic plants are disclosed. In particular, novel recombinant DNA constructs useful in such methods, as well as transgenic plants, cells, and seeds containing such recombinant DNA constructs are provided. The recombinant DNA constructs and the transgenic plants, cells, and seeds containing such constructs provide a greatly improved way to minimize any potential risks that may be associated with expression of insecticidal proteins in male reproductive tissues.
(FR)
L'invention concerne des compositions et des procédés de modulation, par exemple de réduction, de l'expression de protéines insecticides recombinées dans des cellules et/ou des tissus reproducteurs mâles de plantes transgéniques. En particulier, l'invention concerne de nouvelles constructions d'ADN recombiné utiles dans de tels procédés, ainsi que des plantes, des cellules et des graines transgéniques contenant de telles constructions d'ADN recombiné. Les constructions d'ADN recombiné et les plantes, les cellules et les graines transgéniques contenant de telles constructions offrent une manière considérablement améliorée de réduire au minimum tout risque potentiel qui peut être associé à l'expression de protéines insecticides dans les tissus reproducteurs mâles.
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