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1. WO2020198337 - ENGINEERED MRNA SEQUENCES AND USES THEREOF

Publication Number WO/2020/198337
Publication Date 01.10.2020
International Application No. PCT/US2020/024674
International Filing Date 25.03.2020
IPC
C12N 15/67 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
67General methods for enhancing the expression
C12N 5/10 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
10Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
C07K 14/165 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
005from viruses
08RNA viruses
165Coronaviridae, e.g. avian infectious bronchitis virus
Applicants
  • OHIO STATE INNOVATION FOUNDATION [US]/[US]
Inventors
  • DONG, Yizhou
  • ZENG, Chunxi
  • ZHAO, Weiyu
Agents
  • PRATHER, Donald M.
  • HALL, Miles E.
  • MEUNIER, Andrew T.
  • CARLIN, Gregory J.
  • CURFMAN, Christopher L.
Priority Data
62/823,21525.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ENGINEERED MRNA SEQUENCES AND USES THEREOF
(FR) SÉQUENCES D'ARNM MODIFIÉES ET LEURS UTILISATIONS
Abstract
(EN)
The present disclosure relates to a series of engineered mRNA sequences and methods of use for improving protein expression.
(FR)
La présente invention concerne une série de séquences d'ARNm modifiées et des méthodes d'utilisation permettant une amélioration d'expression de protéines.
Latest bibliographic data on file with the International Bureau