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1. WO2020198017 - MULTIPLEXING REGULATORY ELEMENTS TO IDENTIFY CELL-TYPE SPECIFIC REGULATORY ELEMENTS

Publication Number WO/2020/198017
Publication Date 01.10.2020
International Application No. PCT/US2020/023881
International Filing Date 20.03.2020
IPC
C12N 15/861 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
79Vectors or expression systems specially adapted for eukaryotic hosts
85for animal cells
86Viral vectors
861Adenoviral vectors
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
C40B 20/04 2006.01
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
20Methods specially adapted for identifying library members
04Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
C40B 30/00 2006.01
CCHEMISTRY; METALLURGY
40COMBINATORIAL TECHNOLOGY
BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICO LIBRARIES
30Methods of screening libraries
Applicants
  • ENCODED THERAPEUTICS, INC. [US]/[US]
Inventors
  • RAMAMOORTHI, Kartik
  • TANENHAUS, Anne
  • WOOD, Sirika
  • MOORHEAD, Martin
  • TAGLIATELA, Stephanie
  • CHEN, Jerry, S.
  • HOSUR, Raghavendra
Agents
  • VARMA, Anita
  • HEISS, Jacqueline, K.
Priority Data
62/822,52822.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTIPLEXING REGULATORY ELEMENTS TO IDENTIFY CELL-TYPE SPECIFIC REGULATORY ELEMENTS
(FR) MULTIPLEXAGE D'ÉLÉMENTS RÉGULATEURS POUR IDENTIFIER DES ÉLÉMENTS RÉGULATEURS SPÉCIFIQUES DU TYPE CELLULAIRE
Abstract
(EN)
Provided herein is a high-throughput method for screening and identifying regulatory elements that provide selective expression in a particular cell type of interest. Also provided are nucleic acid compositions used in the high-throughput screening method.
(FR)
L'invention concerne un procédé à haut rendement pour cribler et identifier des éléments régulateurs qui fournissent une expression sélective dans un type de cellule particulier d'intérêt. L'invention concerne également des compositions d'acides nucléiques utilisées dans le procédé de criblage à haut rendement.
Latest bibliographic data on file with the International Bureau