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1. WO2020197887 - SURFACE-MODIFIED DOPED TITANIUM DIOXIDE NANOPARTICLES AND USES

Publication Number WO/2020/197887
Publication Date 01.10.2020
International Application No. PCT/US2020/023377
International Filing Date 18.03.2020
IPC
A61K 6/816 2020.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
802comprising ceramics
816comprising titanium oxide
A61K 6/884 2020.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
884comprising natural or synthetic resins
A61K 9/51 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
48Preparations in capsules, e.g. of gelatin, of chocolate
50Microcapsules
51Nanocapsules
A61K 6/20 2020.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
20Protective coatings for natural or artificial teeth, e.g. sealings, dye coatings or varnish
A61K 6/71 2020.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
70comprising inorganic additives
71Fillers
A61K 6/80 2020.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
Applicants
  • THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA [US]/[US]
Inventors
  • FLOREZ, Fernando, Luis Esteban
  • KHAJOTIA, Sharukh, Soli
  • RONDINONE, Adam, Justin
Agents
  • SMITH, Michael, H.
Priority Data
62/822,16122.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SURFACE-MODIFIED DOPED TITANIUM DIOXIDE NANOPARTICLES AND USES
(FR) NANOPARTICULES DE DIOXYDE DE TITANE DOPÉ À SURFACE MODIFIÉE ET LEURS UTILISATIONS
Abstract
(EN)
A titanium dioxide (TiO2) composition and methods of use, the composition containing surface-modified doped TiO2 nanoparticles (sm-TiO2 NPs) disposed in a polymer matrix material, wherein each sm-TiO2 NP has an outer surface having a plurality of bifunctional linker molecules attached thereto and a plurality of protein molecules linked to the sm-TiO2 NP via the bifunctional linker molecules; and wherein the polymer matrix comprises a polymer precursor component.
(FR)
L'invention concerne une composition de dioxyde de titane (TiO2) et des procédés d'utilisation, la composition contenant des nanoparticules de TiO2 dopées modifiées en surface (sm-TiO2 NP) disposées dans un matériau de matrice polymère, chaque sm-TiO2 NP ayant une surface externe ayant une pluralité de molécules de lieur bifonctionnel attachées à celle-ci et une pluralité de molécules protéiques liées aux sm-TiO2 NP par l'intermédiaire des molécules de lieur bifonctionnel ; et la matrice polymère comprenant un composant précurseur de polymère.
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