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1. WO2020197385 - CHITOSAN NITRATE FOR USE AS A NITRIC OXIDE DONOR (NO DONOR)

Publication Number WO/2020/197385
Publication Date 01.10.2020
International Application No. PCT/NL2020/050191
International Filing Date 20.03.2020
IPC
A61K 31/722 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716Glucans
722Chitin; Chitosan
A61K 8/73 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
73Polysaccharides
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61P 9/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
10for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A61P 17/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
CPC
A61K 31/722
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
716Glucans
722Chitin, chitosan
A61K 47/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 8/736
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
72containing organic macromolecular compounds
73Polysaccharides
736Chitin; Chitosan; Derivatives thereof
A61K 9/0014
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0014Skin, i.e. galenical aspects of topical compositions
A61K 9/0031
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0031Rectum, anus
A61K 9/0034
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0034Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
Applicants
  • NO-CEUTICALS B.V. [NL]/[NL]
Inventors
  • RIETJENS, Mathias Hubertus Josephus Maria
Agents
  • NEDERLANDSCH OCTROOIBUREAU
Priority Data
202278822.03.2019NL
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CHITOSAN NITRATE FOR USE AS A NITRIC OXIDE DONOR (NO DONOR)
(FR) NITRATE DE CHITOSANE DESTINÉ À ÊTRE UTILISÉ EN TANT QUE DONNEUR D'OXYDE NITRIQUE (DONNEUR DE NO)
Abstract
(EN)
The present invention relates to chitosan nitrate for use as nitric oxide donor, in particular for use in the prevention or treatment of a condition related to NO deficiency in mammals, preferably humans. Suitable conditions to be treated with chitosan nitrate include disorders related to the skin, conditions related to sexual dysfunction, conditions wherein there is a need for pain treatment, conditions being a disorder related to the eyes, nose and sinus, conditions being a disorder related to the airways, conditions related to a gastro-intestinal disorder, and conditions being a metabolic disorder. These conditions were successfully treated or reduced by the application of chitosan nitrate according to the present invention. The invention also concerns a non-therapeutic or cosmetic method for skin protection and/or for healthy aging.
(FR)
La présente invention concerne du nitrate de chitosane destiné à être utilisé en tant que donneur d'oxyde nitrique, en particulier dans la prévention ou le traitement d'une affection liée à une carence en NO chez des mammifères, de préférence des êtres humains. Des états appropriés à un traitement par nitrate de chitosane comprennent des troubles liés à la peau, des états liés à un dysfonctionnement sexuel, des états où il existe un besoin de traitement de la douleur, les états étant un trouble lié aux yeux, au nez et au sinus, les états étant un trouble lié aux voies respiratoires, les états liés à un trouble gastro-intestinal, et les états étant un trouble métabolique. Ces états ont été traités ou réduits avec succès par l'application de nitrate de chitosane selon la présente invention. L'invention concerne également un procédé non thérapeutique ou cosmétique pour la protection de la peau et/ou pour le vieillissement en bonne santé.
Latest bibliographic data on file with the International Bureau