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1. WO2020197304 - COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING PANCREATIC CANCER, INCLUDING TETRASPANIN-2 INHIBITOR AS ACTIVE INGREDIENT

Publication Number WO/2020/197304
Publication Date 01.10.2020
International Application No. PCT/KR2020/004160
International Filing Date 27.03.2020
IPC
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A23L 33/17 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
17Amino acids, peptides or proteins
G01N 33/50 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
C12Q 1/6886 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
6886for cancer
G01N 33/574 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
574for cancer
Applicants
  • 황정후 HWANG, Jung Hoo [KR]/[KR]
Inventors
  • 황인후 HWANG, In Hu
Agents
  • 이희숙 LEE, Hee Sook
Priority Data
10-2019-003616128.03.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) COMPOSITION FOR PREVENTING, AMELIORATING, OR TREATING PANCREATIC CANCER, INCLUDING TETRASPANIN-2 INHIBITOR AS ACTIVE INGREDIENT
(FR) COMPOSITION VISANT À PRÉVENIR, SOULAGER OU TRAITER LE CANCER DU PANCRÉAS, CONTENANT UN INHIBITEUR DE TÉTRASPANINE-2 EN TANT QUE PRINCIPE ACTIF
(KO) 테트라스파닌-2 억제제를 유효성분으로 포함하는 췌장암 예방, 개선 또는 치료용 조성물
Abstract
(EN)
The present invention relates to a composition which is for preventing, ameliorating, or treating pancreatic cancer, and includes a tetraspanin-2 inhibitor as an active ingredient, and more specifically, to: a composition which is for preventing, ameliorating, or treating pancreatic cancer, and includes an inhibitor of the expression or activity of tetraspanin-2 (TSPAN-2) as an active ingredient; a method for selecting a therapeutic substance for treating pancreatic cancer, by measuring the expression level of TSPAN-2; and a method for providing information useful for diagnosing pancreatic cancer.
(FR)
La présente invention concerne une composition destinée à prévenir, soulager ou traiter le cancer du pancréas qui comprend un inhibiteur de tétraspanine-2 en tant que principe actif et, plus précisément, une composition destinée à prévenir, soulager ou traiter le cancer du pancréas et qui comprend un inhibiteur de l'expression ou de l'activité de tétraspanine-2 (TSPAN-2) en tant que principe actif; une méthode pour sélectionner une substance thérapeutique pour traiter le cancer du pancréas, par mesure du niveau d'expression de TSPAN-2; et une méthode pour fournir des informations utiles pour diagnostiquer un cancer du pancréas.
(KO)
본 발명은 테트라스파닌-2 억제제를 유효성분으로 포함하는 췌장암 예방, 개선 또는 치료용 조성물에 관한 것으로, 보다 상세하게는 테트라스파닌-2(Tetraspanin-2, TSPAN-2)의 발현 또는 활성 억제제를 유효성분으로 포함하는 췌장암 예방, 개선 또는 치료용 조성물, TSPAN-2의 발현 수준을 측정하여 췌장암 치료 물질을 선별하는 방법 및 췌장암 진단에 유용한 정보를 제공하는 방법에 관한 것이다.
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