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1. WO2020197301 - METHOD FOR PREPARATION OF MALTOHEPTAOSE FATTY ACID ESTER AND MALTOHEPTAOSE FATTY ACID ESTER PREPARED THEREBY

Publication Number WO/2020/197301
Publication Date 01.10.2020
International Application No. PCT/KR2020/004153
International Filing Date 26.03.2020
IPC
C12P 19/04 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
19Preparation of compounds containing saccharide radicals
04Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
A01N 43/22 2006.01
AHUMAN NECESSITIES
01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
43Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
02having rings with one or more oxygen or sulfur atoms as the only ring hetero atom
04with one hetero atom
22rings with more than six members
Applicants
  • (주)카보엑스퍼트 CABOEXPERT INC. [KR]/[KR]
Inventors
  • 누엔푸끙 NGUYEN, Phu Cuong
  • 배진주 BAE, Jin Ju
  • 이창규 LEE, Chang Kyu
  • 이난영 LEE, Nan Young
  • 이원희 LEE, Won Hee
  • 반소영 BAN, So Young
  • 박현아 PARK, Hyun Ah
  • 박규빈 PARK, Kyu Been
Agents
  • 특허법인 공간 GHONG-GAN INTERNATIONAL PATENT LAW FIRM
Priority Data
10-2019-003466826.03.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) METHOD FOR PREPARATION OF MALTOHEPTAOSE FATTY ACID ESTER AND MALTOHEPTAOSE FATTY ACID ESTER PREPARED THEREBY
(FR) PROCÉDÉ DE PRÉPARATION D'ESTER D'ACIDE GRAS DE MALTOHEPTAOSE ET ESTER D'ACIDE GRAS DE MALTOHEPTAOSE AINSI PRÉPARÉ
(KO) 말토헵타오스 지방산 에스테르 제조방법 및 이로부터 제조된 말토헵타오스 지방산 에스테르
Abstract
(EN)
The present invention relates to a method for preparation of a maltoheptaose fatty acid ester at high yield and a maltoheptaose fatty acid ester prepared thereby. In the method, an enzyme, which is a biological catalyst, is immobilized to establish an optimal condition, thereby making the process simple and improving reaction selectivity, with the consequent production of the compound at high yield. The maltoheptaose fatty acid ester prepared by the preparation method can be not only used as a drug delivery carrier due to the excellent stability and emulsifying capacity thereof, but also be advantageously applied to an antibacterial composition due to the excellent antibacterial activity thereof.
(FR)
La présente invention concerne un procédé de préparation d'un ester d'acide gras de maltoheptaose à un rendement élevé et un ester d'acide gras de maltoheptaose ainsi préparé. Dans le procédé, une enzyme, qui est un catalyseur biologique, est immobilisée pour établir une condition optimale, ce qui rend le processus simple et améliore la sélectivité de réaction, avec la production conséquente du composé à un rendement élevé. L'ester d'acide gras maltoheptaose préparé par le procédé de préparation peut être non seulement utilisé en tant que support d'administration de médicament en raison de l'excellente stabilité et de sa capacité d'émulsification, mais peut également être avantageusement appliqué à une composition antibactérienne en raison de son excellente activité antibactérienne.
(KO)
본 발명은 말토헵타오스 지방산 에스테르 고수율 제조방법 및 이로부터 제조된 말토헵타오스 지방산 에스테르에 관한 것으로, 생물학적 촉매인 효소를 고정화하여 최적화 조건을 확립함으로써 공정이 간단하고, 반응의 선택성을 높일 수 있어 고수율의 화합물을 생산할 수 있으며, 상기 제조방법으로 제조된 말토헵타오스 지방산 에스테르는 안정성과 유화 용량이 우수하여 약물 전달 담체로 사용될 수 있을뿐 만 아니라 항균 활성이 뛰어나 항균용 조성물로 유용하게 사용할 수 있다.
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