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1. WO2020197101 - DRUG CARRIER FOR DUAL DRUG RELEASE

Publication Number WO/2020/197101
Publication Date 01.10.2020
International Application No. PCT/KR2020/002545
International Filing Date 21.02.2020
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 47/42 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
A61K 47/36 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
A61K 47/34 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
47Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61K 31/573 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573substituted in position 21, e.g. cortisone, dexamethasone, prednisone
Applicants
  • 가톨릭대학교산학협력단 THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION [KR]/[KR]
  • 포항공과대학교 산학협력단 POSTECH ACADEMY-INDUSTRY FOUNDATION [KR]/[KR]
Inventors
  • 원재연 WON, Jae Yon
  • 박영훈 PARK, Young Hoon
  • 조동우 CHO, Dong Woo
  • 김종민 KIM, Jong Min
  • 가오그 GAO, Ge
  • 김지수 KIM, Ji Soo
  • 장진아 JANG, Jin Ah
Agents
  • 특허법인 이룸리온 ERUUM & LEEON INTELLECTUAL PROPERTY LAW FIRM
Priority Data
10-2019-003447926.03.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) DRUG CARRIER FOR DUAL DRUG RELEASE
(FR) SUPPORT DE MÉDICAMENT POUR LA LIBÉRATION DE DEUX MÉDICAMENTS
(KO) 이중 약물 방출을 위한 약물 전달체
Abstract
(EN)
The present invention relates to a drug carrier for dual drug release and, more specifically, to a drug carrier wherein, by a structure of: a core rod in which a first drug and a first biocompatible polymer are mixed; and a shell in which a second drug and a second biocompatible polymer are mixed, a drug can be sequentially released and can also be continuously released. According to the drug carrier according to the present invention, a dual drug can be sequentially/continuously released, and thus, the number of times of drug administration can be reduced, and accordingly, side effects can also be minimized.
(FR)
La présente invention concerne un support de médicament pour une libération de médicament double et, plus spécifiquement, un support de médicament dans lequel, -au moyen d'une structure formée: d'une tige centrale dans laquelle un premier médicament et un premier polymère biocompatible sont mélangés; et d'une coque dans laquelle un second médicament et un second polymère biocompatible sont mélangés-, un médicament peut être libéré de manière séquentielle et peut également être libéré en continu. Avec le support de médicament selon la présente invention, un médicament double peut être libéré de manière séquentielle/continue, et ainsi, le nombre de fois où se produit l'administration de médicament peut être réduit, et par conséquent, les effets secondaires peuvent également être réduits au minimum.
(KO)
본 발명은 이중 약물 방출을 위한 약물 전달체에 관한 것으로, 더욱 상세하게는 제1 약물과 제1 생체 적합성 고분자가 혼합된 코어 로드(core rod) 및, 제2 약물과 제2 생체 적합성 고분자가 혼입된 쉘(shell) 구조에 의해 약물이 순차적으로 방출될 뿐만 아니라 지속적으로 방출될 수 있는 약물 전달체에 관한 것이다. 본 발명에 따른 약물 전달체에 따르면, 이중 약물이 순차적/지속적으로 방출될 수 있도록 함으로써 약물 투여 횟수를 줄일 수 있으며, 이에 따라 부작용도 최소화할 수 있다.
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