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1. WO2020196953 - PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING OSTEOCALCIN

Publication Number WO/2020/196953
Publication Date 01.10.2020
International Application No. PCT/KR2019/003555
International Filing Date 27.03.2019
IPC
A61K 38/22 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17from animals; from humans
22Hormones
A61P 29/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
29Non-central analgesic, antipyretic or antiinflammatory agents, e.g antirheumatic agents; Non-steroidal antiinflammatory drugs (NSAIDs)
A61P 19/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
02for joint disorders, e.g. arthritis, arthrosis
A23L 33/17 2016.01
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
17Amino acids, peptides or proteins
Applicants
  • 주식회사 제너로스 GENEROATH CO.,LTD. [KR]/[KR]
Inventors
  • 백경화 BAEK, Kyunghwa
  • 박단비 PARK, Danbi
Agents
  • 위병갑 WIE, Byoung-Gap
Priority Data
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING INFLAMMATORY DISEASES, COMPRISING OSTEOCALCIN
(FR) COMPOSITION PHARMACEUTIQUE, POUR LA PRÉVENTION OU LE TRAITEMENT DE MALADIES INFLAMMATOIRES, COMPRENANT DE L'OSTÉOCALCINE
(KO) 오스테오칼신을 포함하는 염증성 질환의 예방 또는 치료용 약학 조성물
Abstract
(EN)
The present invention relates to a pharmaceutical composition for effectively preventing or treating inflammatory diseases. A pharmaceutical composition comprising undercarboxylated osteocalcin according to the present invention can effectively inhibit the production of TNF-α, IL-1β or IL-6 which are inflammatory cytokine, and thus can be utilized in various industry fields such as drugs and foods as a substance for preventing, treating or alleviating various inflammatory diseases.
(FR)
La présente invention concerne une composition pharmaceutique pour prévenir ou traiter efficacement des maladies inflammatoires. Une composition pharmaceutique comprenant de l'ostéocalcine sous-carboxylée selon la présente invention peut inhiber efficacement la production de TNF-α, d'IL-1β ou d'IL-6 qui sont des cytokines inflammatoires, et peut ainsi être utilisée dans divers domaines industriels tels que des médicaments et des aliments en tant que substance pour prévenir, traiter ou soulager diverses maladies inflammatoires.
(KO)
본 발명의 염증성 질환을 효과적으로 예방하거나 치료할 수 있는 약학적 조성물에 관한 것이다. 본 발명에 따른 저카르복실화 오스테오칼신을 포함하는 약학적 조성물은 염증성 사이토카인인 TNF-α, IL-1β 또는 IL-6의 생성을 효과적으로 억제할 수 있으므로, 각종 염증성 질환을 예방, 치료 또는 개선할 수 있는 물질로서 의약품, 식품과 같은 다양한 산업 분야에 유용하게 사용될 수 있다.
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