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1. WO2020196926 - CELL COMPETITION INHIBITOR

Publication Number WO/2020/196926
Publication Date 01.10.2020
International Application No. PCT/JP2020/014715
International Filing Date 30.03.2020
IPC
A61K 45/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A61P 21/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
21Drugs for disorders of the muscular or neuromuscular system
02Muscle relaxants, e.g. for tetanus or cramps
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 25/14 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
14for treating abnormal movements, e.g. chorea, dyskinesia
A61P 25/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
14for treating abnormal movements, e.g. chorea, dyskinesia
16Anti-Parkinson drugs
A61P 25/28 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
28for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applicants
  • 学校法人早稲田大学 WASEDA UNIVERSITY [JP]/[JP]
Inventors
  • 丸山 剛 MARUYAMA, Takeshi
Agents
  • 高島 一 TAKASHIMA, Hajime
Priority Data
2019-06359428.03.2019JP
2019-06977701.04.2019JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) CELL COMPETITION INHIBITOR
(FR) INHIBITEUR DE COMPÉTITION CELLULAIRE
(JA) 細胞競合の制御剤
Abstract
(EN)
The present invention provides a cell competition inhibitor comprising an agonist antibody, which is directed against a protein containing the α3 domain of MHC class Ia or LILRB3, or a substance which inhibits the binding of LILRB3 to MHC class Ia.
(FR)
La présente invention concerne un inhibiteur de compétition cellulaire comprenant un anticorps agoniste, qui est dirigé contre une protéine contenant le domaine α3 de classe Ia du CMH ou LILRB3, ou une substance qui inhibe la liaison de LILRB3 à la classe Ia du CMH.
(JA)
本発明は、MHC class Iaのα3ドメインを含むタンパク質若しくはLILRB3に対するアゴニスト抗体、又はMHC class IaとLILRB3との結合を阻害する物質を含む、細胞競合の制御剤を提供する。
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