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1. WO2020196736 - RNAI MOLECULE

Publication Number WO/2020/196736
Publication Date 01.10.2020
International Application No. PCT/JP2020/013623
International Filing Date 26.03.2020
IPC
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 35/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
02specific for leukemia
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
C12N 5/09 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
09Tumour cells
C12N 15/113 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
15Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
09Recombinant DNA-technology
11DNA or RNA fragments; Modified forms thereof
113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
Applicants
  • 日東電工株式会社 NITTO DENKO CORPORATION [JP]/[JP]
Inventors
  • 田中 洋行 TANAKA Hiroyuki
  • 高橋 博一 TAKAHASHI Hirokazu
  • 高木 義和 TAKAGI Yoshikazu
  • 味呑 憲二郎 MINOMI Kenjiro
Agents
  • 小林 浩 KOBAYASHI Hiroshi
  • 三橋 規樹 MITSUHASHI Motoki
  • 鈴木 康仁 SUZUKI Yasuhito
Priority Data
2019-06444328.03.2019JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) RNAI MOLECULE
(FR) MOLÉCULE D'ARNI
(JA) RNAi分子
Abstract
(EN)
Provided are: an RNAi molecule whose antisense chain contains the nucleotide sequence of SEQ ID NO: 1; and a method for treating a disease, which comprises administration of an effective dose of this RNAi molecule to a subject requiring the molecule.
(FR)
L'invention concerne : une molécule d'ARNi dont la chaîne antisens contient la séquence nucléotidique de SEQ ID NO : 1 ; et une méthode de traitement d'une maladie, qui comprend l'administration d'une dose efficace de cette molécule d'ARNi à un sujet nécessitant la molécule.
(JA)
配列番号1のヌクレオチド配列をアンチセンス鎖に含む、RNAi分子、有効量の前記RNAi分子を、それを必要とする対象に投与することを含む、疾患を処置する方法。
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