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1. WO2020196725 - AGENT FOR IMPROVING NERVE AXON BRANCHING ANOMALIES

Publication Number WO/2020/196725
Publication Date 01.10.2020
International Application No. PCT/JP2020/013602
International Filing Date 26.03.2020
IPC
A61K 45/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/-A61K41/132
A61K 48/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
48Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
A61P 43/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
A61K 31/42 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
42Oxazoles
A61K 31/7088 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7088Compounds having three or more nucleosides or nucleotides
Applicants
  • 一般財団法人生産技術研究奨励会 THE FOUNDATION FOR THE PROMOTION OF INDUSTRIAL SCIENCE [JP]/[JP]
Inventors
  • 青木 正志 AOKI, Masashi
  • 鈴木 直輝 SUZUKI, Naoki
  • 秋山 徹也 AKIYAMA, Tetsuya
  • 割田 仁 WARITA, Hitoshi
  • 岡野 栄之 OKANO, Hideyuki
  • 藤井 輝夫 FUJII, Teruo
  • 池内 与志穂 IKEUCHI, Yoshiho
  • 川田 治良 KAWADA, Jiro
Agents
  • 廣田 雅紀 HIROTA, Masanori
Priority Data
2019-06087627.03.2019JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) AGENT FOR IMPROVING NERVE AXON BRANCHING ANOMALIES
(FR) AGENT POUR ATTÉNUER DES ANOMALIES DE RAMIFICATION D'AXONE NERVEUX
(JA) 神経軸索分岐異常の改善剤
Abstract
(EN)
The present invention addresses the problem of providing a substance having the effect of improving nerve axon branching anomalies. In the present invention, motor neuron axon branching anomalies can be improved by administering an AP-1 inhibitor.
(FR)
Le problème décrit par la présente invention est de fournir une substance ayant pour effet d'atténuer des anomalies de ramification d'axone nerveux. Selon la présente invention, des anomalies de ramification d'axone de neurone moteur peuvent être atténuées par l'administration d'un inhibiteur d'AP-1.
(JA)
本発明は、神経軸索分岐異常を改善する作用を有する物質を提供することを課題とする。 AP-1阻害剤を投与すると、運動ニューロンにおける軸索の分岐異常を改善することができる。
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