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1. WO2020194245 - CLINICALLY PROVEN SUBCUTANEOUS PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND THEIR USES IN COMBINATION WITH BORTEZOMIB, MELPHALAN AND PREDNISONE

Publication Number WO/2020/194245
Publication Date 01.10.2020
International Application No. PCT/IB2020/052888
International Filing Date 26.03.2020
IPC
A61K 9/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 31/573 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
56Compounds containing cyclopentahydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
57substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane, progesterone
573substituted in position 21, e.g. cortisone, dexamethasone, prednisone
A61K 38/47 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38Medicinal preparations containing peptides
16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
43Enzymes; Proenzymes; Derivatives thereof
46Hydrolases (3)
47acting on glycosyl compounds (3.2), e.g. cellulases, lactases
C07K 16/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
Applicants
  • JANSSEN BIOTECH, INC. [US]/[US]
Inventors
  • BANDEKAR, Rajesh
  • CLEMENS, Pamela
  • HEUCK, Christoph
  • QI, Ming
  • YUAN, Zhilong
Agents
  • SHIRTZ, Joseph F.
  • BAUMEISTER, Kirk
Priority Data
62/825,29028.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CLINICALLY PROVEN SUBCUTANEOUS PHARMACEUTICAL COMPOSITIONS COMPRISING ANTI-CD38 ANTIBODIES AND THEIR USES IN COMBINATION WITH BORTEZOMIB, MELPHALAN AND PREDNISONE
(FR) COMPOSITIONS PHARMACEUTIQUES SOUS-CUTANÉES CLINIQUEMENT ÉPROUVÉES COMPRENANT DES ANTICORPS ANTI-CD38 ET LEURS UTILISATIONS EN ASSOCIATION AVEC DU BORTÉZOMIB, DU MELPHALAN ET DE LA PREDNISONE
Abstract
(EN)
The present invention relates to clinically proven subcutaneous pharmaceutical compositions comprising anti-CD38 antibodies and methods of their uses in combination with bortezomib, melphalan and prednisone.
(FR)
La présente invention concerne des compositions pharmaceutiques sous-cutanées cliniquement éprouvées comprenant des anticorps anti-CD38 et leurs procédés d'utilisation en association avec du bortézomib, du melphalan et de la prednisone.
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