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1. WO2020193660 - IMIDAZOLONYLQUINOLINE COMPOUNDS AND THERAPEUTIC USES THEREOF


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2020/058425 P19-052WOPCT
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
25 March 2020 27 March 2019
Applicant
MERCK PATENT GMBH
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No. ____________
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     C07D 471/04 (2006.01)i; A61P 35/00 (2006.01)i; A61K 31/4375 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     C07D; A61P
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data, CHEM ABS Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
X
WO 2016155884 A1 (MERCK PATENT GMBH [DE]) 06 October 2016 (2016-10-06)
3,7
cited in the application
A
claims; examples 4, 150; tables 2-3
1,2,4-6,8-15
(2)
A
DAVIS E. SMITH ET AL, "Exploiting Atropisomerism to Increase the Target Selectivity of Kinase Inhibitors", ANGEWANDTE CHEMIE, INTERNATIONAL EDITION,Vol. 54, No. 40, 28 September 2015 (2015-09-28), page 11754-11759,
XP055528613
1-15
the whole document
(3)
A
KENYU YOSHIDA ET AL, "Synthesis, Resolution, and Biological Evaluation of Atropisomeric (a R )- and (a S )-16-Methyllamellarins N: Unique Effects of the Axial Chirality on the Selectivity of Protein Kinases Inhibition", JOURNAL OF MEDICINAL CHEMISTRY,Vol. 56, No. 18, 01 January 2013 (2013-01-01), page 7289-7301,
XP055637432
1-15
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
WO 2016155884 A1
06 October 2016
AU 2016239270 A1
BR 112017020941 A2
CA 2981365 A1
CN 107889488 A
DK 3277681 T3
EP 3277681 A1
EP 3560924 A1
ES 2741853 T3
HR P20191396 T1
HU E045477 T2
IL 254714 A
JP 2018510191 A
KR 20170132323 A
LT 3277681 T
PL 3277681 T3
PT 3277681 T
RU 2017138100 A
SG 11201708065Q A
SI 3277681 T1
TR 201911244 T4
US 2018072715 A1
US 2019211013 A1
WO 2016155884 A1
16 November 2017
10 July 2018
06 October 2016
06 April 2018
29 July 2019
07 February 2018
30 October 2019
12 February 2020
01 November 2019
30 December 2019
30 January 2020
12 April 2018
01 December 2017
12 August 2019
31 October 2019
20 August 2019
08 May 2019
30 October 2017
30 September 2019
21 August 2019
15 March 2018
11 July 2019
06 October 2016
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
12 May 2020
Date of mailing of the international search report:
03 June 2020
Authorized officer:
Gavriliu, Daniela
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