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1. WO2020193549 - SLICE ALIGNMENT FOR SHORT AXIS CARDIAC MR CINE SLICE STACKS


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INTERNATIONAL SEARCH REPORT (ISR)
Part 1:  1  2  3  4  5  6          Part 2:  A  B  C  D  E 
International application No. Applicant's or agent's file reference
PCT/EP2020/058156 2019P00070WO
International filing date (day/month/year) (Earliest) Priority Date (day/month/year)
24 March 2020 27 March 2019
Applicant
KONINKLIJKE PHILIPS N.V.
FOR FURTHER ACTION: See Form PCT/ISA/220 as well as, where applicable, item 5 below.
This international search report has been prepared by this International Searching Authority and is transmitted to the applicant according to Article 18. A copy is being transmitted to the International Bureau.
It is also accompanied by a copy of each prior art document cited in this report.
1. Basis of the report
a. With regard to the language, the international search was carried out on the basis of:
the international application in the language in which it was filed.
a translation of the international application into                                          which is the language of a translation furnished for the purposes of international search (Rules 12.3(a) and 23.1(b)).
b.
This international search report has been established taking into account the rectification of an obvious mistake authorized by or notified to this Authority under Rule 91 (Rule 43.6bis(a)).
c.
With regard to any nucleotide and/or amino acid sequence disclosed in the international application, the international search was carried out on the basis of a sequence listing:
2. Certain claims were found unsearchable
3. Unity of invention is lacking
This International Searching Authority found multiple inventions in this international application, as follows:
1. claims: 1-8, 13(completely); 15(partially)
A system, a computer-readable medium, a computer-implemented method and a further computer-readable medium for slice alignment of short axis cardiac magnetic resonance cine slice stacks comprising a machine trained model configured and trained to be applied to a set of adjacent image slices of a set of image slices acquired using a short axis cardiac magnetic resonance cine protocol, wherein the machine trained model is trained to output a shift value if the set of adjacent image slices is mutually misaligned for reducing mutual misalignment.
2. claims: 9-12, 14(completely); 15(partially)
A system, a computer-implemented method and a computer-readable medium for slice alignment of short axis cardiac magnetic resonance cine slice stacks comprising accessing surface model data defining a deformable surface model for segmenting a cardiac structure in short axis cardiac MR cine slice stacks, wherein deformability of the surface model is constrained by shape regularization; adapting the surface model to the cardiac structure by detecting boundary points of the cardiac structure in the image data and deforming the surface model towards the boundary points to obtain an adapted surface model which is adapted in shape to the cardiac structure in the image data; and shifting at least one image slice relative to other image slices so that the boundary points in the image slice obtain an improved match with a cross-sectional representation of the surface model in the respective image slice.
1.
As all required additional search fees were timely paid by the applicant, this international search report covers all searchable claims.
2.
As all searchable claims could be searched without effort justifying additional fees, this Authority did not invite payment of additional fees.
3.
As only some of the required additional search fees were timely paid by the applicant, this international search report covers only those claims for which fees were paid, specifically claims Nos.:
4.
No required additional search fees were timely paid by the applicant. Consequently, this international search report is restricted to the invention first mentioned in the claims; it is covered by claims Nos.: 1-8, 13(completely); 15(partially)
Remark on Protest
The additional search fees were accompanied by the applicant’s protest and, where applicable, the payment of a protest fee.
The additional search fees were accompanied by the applicant’s protest but the applicable protest fee was not paid within the time limit specified in the invitation.
No protest accompanied the payment of additional search fees.
4. Title of the invention
The text is approved as submitted by the applicant.
The text has been established by this Authority to read as follows:
5. Abstract
The text is approved as submitted by the applicant.
The text has been established, according to Rule 38.2, by this Authority as it appears in Box No. IV. The applicant may, within one month from the date of mailing of this international search report, submit comments to this Authority.
6. Drawings
a.
The figure of the drawings to be published with the abstract is Figure No.     4    
as suggested by the applicant.
as selected by this Authority, because the applicant failed to suggest a figure.
as selected by this Authority, because this figure better characterizes the invention.
b.
none of the figures is to be published with the abstract.

A. CLASSIFICATION OF SUBJECT MATTER

     G01R 33/563 (2006.01)i; G01R 33/483 (2006.01)i; G01R 33/565 (2006.01)i; A61B 5/00 (2006.01)i
According to International Patent Classification (IPC) or to both national classification and IPC

B. FIELDS SEARCHED

Minimum documentation searched (classification system followed by classification symbols):
     G01R; A61B
Documentation searched other than minimum documentation to the extent that such documents are included in the fields searched:
Electronic data base consulted during the international search (name of data base and, where practicable, search terms used):
EPO-Internal, WPI Data

C. DOCUMENTS CONSIDERED TO BE RELEVANT

Category* Citation of document, with indication, where appropriate, of the relevant passages Relevant to claim No.
(1)
A
FADIL HAKIM ET AL, "4D Automatic Centre Detection of the Right and Left Ventricles from Cine Short-Axis MRI", 24 January 2017 (2017-01-24), INTERNATIONAL CONFERENCE ON COMPUTER ANALYSIS OF IMAGES AND PATTERNS. CAIP 2017: COMPUTER ANALYSIS OF IMAGES AND PATTERNS; [LECTURE NOTES IN COMPUTER SCIENCE; LECT.NOTES COMPUTER], SPRINGER, BERLIN, HEIDELBERG, PAGE(S) 143 - 151,
XP047395764
ISBN: 9783642173189
1-8,13,15
pages 143, 149; figure 8
(2)
X
OKTAY O ET AL, "Respiratory motion correction for 2D cine cardiac MR images using probabilistic edge maps", 2016 COMPUTING IN CARDIOLOGY CONFERENCE (CINC), CCAL,11 September 2016 (2016-09-11), page 129-132,
XP033071168
1-8,13,15
page 129 - page 131; figure 2
(3)
X
DANGI SHUSIL ET AL, "Cine cardiac MRI slice misalignment correction towards full 3D left ventricle segmentation", PROGRESS IN BIOMEDICAL OPTICS AND IMAGING, SPIE - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, BELLINGHAM, WA, US,Vol. 10576, 12 March 2018 (2018-03-12), page 1057607-1057607,
XP060106748
ISBN: 9781510600270
1,2,7,8,13,15
page 2 - page 4; figures 1, 2
(4)
A
US 2017109881 A1 (AVENDI MICHAEL RASHIDI [US] ET AL) 20 April 2017 (2017-04-20)
1-8,13,15
cited in the application
the whole document
(5)
A
KERFOOT ERIC ET AL, "Automated CNN-Based Reconstruction of Short-Axis Cardiac MR Sequence from Real-Time Image Data", 12 September 2018 (2018-09-12), 12TH EUROPEAN CONFERENCE ON COMPUTER VISION, ECCV 2012; [LECTURE NOTES IN COMPUTER SCIENCE], SPRINGER BERLIN HEIDELBERG, BERLIN, HEIDELBERG, PAGE(S) 32 - 41,
XP047526320
ISBN: 9783540377832
1-8,13,15
the whole document
(6)
A
ZOTTI CLEMENT ET AL, "Convolutional Neural Network With Shape Prior Applied to Cardiac MRI Segmentation", 14 August 2018 (2018-08-14), Vol. 23, No. 3, page 1119-1128,
XP011722618
[retrieved on  2019-05-02]
1-8,13,15
the whole document
*
Special categories of cited documents:
"A"
document defining the general state of the art which is not considered to be of particular relevance
"D"
document cited by the applicant in the international application
"E"
earlier application or patent but published on or after the international filing date
"L"
document which may throw doubts on priority claim(s) or which is cited to establish the publication date of another citation or other special reason (as specified)
"O"
document referring to an oral disclosure, use, exhibition or other means
"P"
document published prior to the international filing date but later than the priority date claimed
"T"
later document published after the international filing date or priority date and not in conflict with the application but cited to understand the principle or theory underlying the invention
"X"
document of particular relevance; the claimed invention cannot be considered novel or cannot be considered to involve an inventive step when the document is taken alone
"Y"
document of particular relevance; the claimed invention cannot be considered to involve an inventive step when the document is combined with one or more other such documents, such combination being obvious to a person skilled in the art
"&"
document member of the same patent family

D. INFORMATION ON PATENT FAMILY MEMBERS

Patent document cited in search report Publication date
(day/month/year)
Patent family member(s) Publication date
(day/month/year)
US 2017109881 A1
20 April 2017
US 2017109881 A1
US 2020118266 A1
20 April 2017
16 April 2020
Name and mailing address of the ISA/:
European Patent Office
P.B. 5818, Patentlaan 2, 2280 HV Rijswijk,
Netherlands
Telephone No. (+31-70)340-2040
Facsimile No. (+31-70)340-3016
Date of the actual completion of the international search:
09 June 2020
Date of mailing of the international search report:
14 August 2020
Authorized officer:
Raguin, Guy
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