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1. WO2020193407 - USE OF MURAMIC ACID AS A BIOMARKER FOR GASTROINTESTINAL PEPTIDOGLYCAN HYDROLYSIS

Publication Number WO/2020/193407
Publication Date 01.10.2020
International Application No. PCT/EP2020/057780
International Filing Date 20.03.2020
IPC
C12N 9/24 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes, e.g. ligases (6.); Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating, or purifying enzymes
14Hydrolases (3.)
24acting on glycosyl compounds (3.2)
CPC
C12N 9/24
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
9Enzymes; Proenzymes; Compositions thereof
14Hydrolases (3)
24acting on glycosyl compounds (3.2)
Applicants
  • NOVOZYMES A/S [DK]/[DK]
Inventors
  • KLAUSEN, Mikkel
  • FREDERIKSEN, Carsten, Oestergaard
Priority Data
19164624.922.03.2019EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) USE OF MURAMIC ACID AS A BIOMARKER FOR GASTROINTESTINAL PEPTIDOGLYCAN HYDROLYSIS
(FR) UTILISATION D'ACIDE MURAMIQUE COMME BIOMARQUEUR POUR L'HYDROLYSE DE PEPTIDOGLYCANE GASTRO-INTESTINAL
Abstract
(EN)
Muramic acid measurements in acid hydrolysed digesta samples are used to measure the activity of peptidoglycan hydrolyzing enzyme, as illustrated by the use of a muramidase, as determined by the degree of peptidoglycan hydrolysis, in the gastrointestinal tract of animals fed supplements with the muramidase.
(FR)
Des mesures d'acide muramique dans des échantillons de digesta hydrolysés par un acide sont utilisées pour mesurer l'activité de l'enzyme hydrolysant le peptidoglycane, comme illustré par l'utilisation d'une muramidase, telle que déterminée par le degré d'hydrolyse de peptidoglycane, dans le tractus gastro-intestinal des animaux nourris avec la muramidase.
Latest bibliographic data on file with the International Bureau