Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020191501 - METHODS AND USES OF BEMITHYL AND DERIVATIVES FOR TREATING LUNG DISEASE, FATTY LIVER DISEASE, AND KIDNEY DISORDERS

Publication Number WO/2020/191501
Publication Date 01.10.2020
International Application No. PCT/CA2020/050407
International Filing Date 27.03.2020
IPC
A61K 31/4184 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
41having five-membered rings with two or more ring hetero atoms, at least one of which is nitrogen, e.g. tetrazole
41641,3-Diazoles
4184condensed with carbocyclic rings, e.g. benzimidazoles
A61P 1/16 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
1Drugs for disorders of the alimentary tract or the digestive system
16for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 11/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
11Drugs for disorders of the respiratory system
A61P 13/12 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
13Drugs for disorders of the urinary system
12of the kidneys
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07D 235/28 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
28Sulfur atoms
Applicants
  • ALGERNON PHARMACEUTICALS INC. [CA]/[CA]
Inventors
  • WILLIAMS, Mark
Agents
  • RIDOUT & MAYBEE LLP
  • HELLER, David
Priority Data
62/824,73827.03.2019US
62/940,56626.11.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHODS AND USES OF BEMITHYL AND DERIVATIVES FOR TREATING LUNG DISEASE, FATTY LIVER DISEASE, AND KIDNEY DISORDERS
(FR) PROCÉDÉS ET UTILISATIONS DE BÉMITHYLE ET DE DÉRIVÉS POUR LE TRAITEMENT D'UNE MALADIE PULMONAIRE, D'UNE STÉATOSE HÉPATIQUE ET DE TROUBLES RÉNAUX
Abstract
(EN)
Methods and uses of bemithyl and derivatives of the formula (I) for treating fibrotic diseases are taught, and in particular, chronic lung disease, including idiopathic pulmonary fibrosis; non-alcoholic fatty liver disease, and in particular, non-alcoholic fatty liver, and non-alcoholic steatohepatitis; and kidney disorders, and in particular, renal fibrosis and/or chronic kidney disease.
(FR)
L'invention concerne des procédés et des utilisations de bémithyle et de dérivés de formule (I) pour le traitement de maladies fibrotiques, et en particulier, une maladie pulmonaire chronique, notamment la fibrose pulmonaire idiopathique ; une maladie du foie stéatosique non alcoolique, et en particulier, un foie stéatosique non alcoolique, et la stéatohépatite non alcoolique ; et des troubles rénaux, et en particulier, une fibrose rénale et/ou une maladie rénale chronique.
Latest bibliographic data on file with the International Bureau