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1. WO2020191448 - A SALT AND CRYSTAL FORM OF A FAK INHIBITOR

Publication Number WO/2020/191448
Publication Date 01.10.2020
International Application No. PCT/AU2020/050292
International Filing Date 27.03.2020
IPC
C07D 401/12 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61K 31/506 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
506not condensed and containing further heterocyclic rings
Applicants
  • AMPLIA THERAPEUTICS LIMITED [AU]/[AU]
Inventors
  • BURNS, Christopher
  • LAMBERT, John
Agents
  • FPA PATENT ATTORNEYS PTY LTD
Priority Data
201990105028.03.2019AU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A SALT AND CRYSTAL FORM OF A FAK INHIBITOR
(FR) SEL ET FORME CRISTALLINE D'UN INHIBITEUR DE FAK
Abstract
(EN)
The present invention is directed to the tartrate salt of a FAK inhibitor defined by formula (I) below, and the use of that inhibitor for treating a proliferative disease.
(FR)
La présente invention concerne le sel de tartrate d'un inhibiteur de FAK défini par la formule (I) ci-dessous, et l'utilisation de cet inhibiteur pour traiter une maladie proliférative.
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