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1. WO2020191434 - ANTI-HER2 BINDING MOLECULES

Publication Number WO/2020/191434
Publication Date 01.10.2020
International Application No. PCT/AU2020/050274
International Filing Date 20.03.2020
IPC
C07K 16/30 2006.01
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
30from tumour cells
A61K 39/395 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 35/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
Applicants
  • OLIVIA NEWTON-JOHN CANCER RESEARCH INSTITUTE [AU]/[AU]
Inventors
  • SCOTT, Andrew Mark
  • GAN, Hui Kong
  • LIU, Zhanqi
  • PARAKH, Sagun
Agents
  • FB RICE PTY LTD
Priority Data
201990097322.03.2019AU
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-HER2 BINDING MOLECULES
(FR) MOLÉCULES DE LIAISON ANTI-HER2
Abstract
(EN)
The present disclosure is directed to binding proteins to the extracellular domain (ECD) of HER2/ErbB2. More particularly, the binding proteins bind to a conformational epitope which is exposed in cells in response to HER2 amplification or activation.
(FR)
La présente invention concerne des protéines de liaison au domaine extracellulaire (ECD) de HER2/ErbB2. Plus particulièrement, les protéines de liaison se lient à un épitope conformationnel qui est exposé dans des cellules en réponse à une amplification ou une activation de HER2.
Latest bibliographic data on file with the International Bureau