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1. WO2020185828 - DETECTION OF PHARMACEUTICAL PRODUCT FREEZING HISTORY USING WATER PROTON NMR

Publication Number WO/2020/185828
Publication Date 17.09.2020
International Application No. PCT/US2020/021983
International Filing Date 11.03.2020
IPC
A61K 39/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
G01N 24/08 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
24Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
08by using nuclear magnetic resonance
CPC
A61K 39/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
G01N 24/08
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
24Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
08by using nuclear magnetic resonance
Applicants
  • UNIVERSITY OF MARYLAND, BALTIMORE [US]/[US] (AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BE, BF, BG, BH, BJ, BN, BR, BW, BY, BZ, CA, CF, CG, CH, CI, CL, CM, CN, CO, CR, CU, CY, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, FR, GA, GB, GD, GE, GH, GM, GN, GQ, GR, GT, GW, HN, HR, HU, ID, IE, IL, IN, IR, IS, IT, JO, JP, KE, KG, KH, KM, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LT, LU, LV, LY, MA, MC, MD, ME, MG, MK, ML, MN, MR, MT, MW, MX, MY, MZ, NA, NE, NG, NI, NL, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SI, SK, SL, SM, SN, ST, SV, SY, SZ, TD, TG, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, UZ, VC, VN, WS, ZA, ZM, ZW)
  • YU, Yihua Bruce [US]/[US] (US)
  • TARABAN, Marc B. [US]/[US] (US)
  • BRIGGS, Katharine T. [US]/[US] (US)
Inventors
  • YU, Yihua Bruce
  • TARABAN, Marc B.
  • BRIGGS, Katharine T.
Agents
  • FUIERER, Tristan A.
Priority Data
62/816,43611.03.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) DETECTION OF PHARMACEUTICAL PRODUCT FREEZING HISTORY USING WATER PROTON NMR
(FR) DÉTECTION D'UN HISTORIQUE DE CONGÉLATION DE PRODUIT PHARMACEUTIQUE À L'AIDE D'UNE RMN DES PROTONS DE L'EAU
Abstract
(EN)
A method of using the relaxation rate (R1 and/or R2) of solvent NMR signal to invasively or noninvasively assess whether vaccines and other aqueous-based pharmaceutical products have been frozen during transport and/or storage.
(FR)
L'invention concerne un procédé d'utilisation du taux de relaxation (R 1 et/ou R 2 ) du signal RMN du solvant pour évaluer de manière invasive ou non invasive si des vaccins et d'autres produits pharmaceutiques à base aqueuse ont été congelés pendant le transport et/ou le stockage.
Latest bibliographic data on file with the International Bureau