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1. WO2020167567 - HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF AMYLOID-RELATED DISEASES

Publication Number WO/2020/167567
Publication Date 20.08.2020
International Application No. PCT/US2020/016934
International Filing Date 06.02.2020
IPC
C07D 235/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
235Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
02condensed with carbocyclic rings or ring systems
04Benzimidazoles; Hydrogenated benzimidazoles
24with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
28Sulfur atoms
C07D 401/12 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
401Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
C07D 487/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/-C07D477/183
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
CPC
C07D 471/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
471Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
C07D 487/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
487Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by C07D451/00 - C07D477/00
02in which the condensed system contains two hetero rings
04Ortho-condensed systems
Applicants
  • D.E. SHAW RESEARCH, LLC [US]/[US]
Inventors
  • GIORDANETTO, Fabrizio
  • CAMPBELL-BEZAT, Cecily
  • PAN, Albert
Agents
  • SUPERKO, Colleen
  • BERTULLI, Scott
  • ANDERSON, Thomas, E.
  • BLAKELY, Laurem, V.
  • BEVILACQUA, Michael, J.
Priority Data
62/803,66311.02.2019US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) HETEROCYCLIC COMPOUNDS AND THEIR USE IN THE TREATMENT OF AMYLOID-RELATED DISEASES
(FR) COMPOSÉS HÉTÉROCYCLIQUES ET LEUR UTILISATION DANS LE TRAITEMENT DE MALADIES LIÉES AUX AMYLOÏDES
Abstract
(EN) A compound of Formula (I) or a pharmaceutically acceptable salt thereof is described, wherein the substituents are as defined herein. Pharmaceutical compositions comprising the same and method of using the same are also described.
(FR) L'invention concerne un composé de formule (I) ou un sel pharmaceutiquement acceptable de celui-ci, les substituants étant tels que définis dans la description. L'invention concerne également des compositions pharmaceutiques les comprenant et un procédé d'utilisation de celles-ci.
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