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1. WO2020150445 - A METHOD TO QUANTIFY THE HEMODYNAMIC AND VASCULAR PROPERTIES IN VIVO FROM ARTERIAL WAVEFORM MEASUREMENTS

Publication Number WO/2020/150445
Publication Date 23.07.2020
International Application No. PCT/US2020/013830
International Filing Date 16.01.2020
IPC
A61B 5/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
A61B 5/0205 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
A61B 5/021 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
021Measuring pressure in heart or blood vessels
A61B 5/0215 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
021Measuring pressure in heart or blood vessels
0215by means inserted into the body
A61B 5/022 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
021Measuring pressure in heart or blood vessels
022by applying pressure to close blood vessels, e.g. against the skin; Ophthaldynamometers
A61B 5/024 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
024Measuring pulse rate or heart rate
CPC
A61B 2562/0261
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2562Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
02Details of sensors specially adapted for in-vivo measurements
0261Strain gauges
A61B 5/02007
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
02007Evaluating blood vessel condition, e.g. elasticity, compliance
A61B 5/02028
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
02028Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
A61B 5/02108
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
021Measuring pressure in heart or blood vessels
02108from analysis of pulse wave characteristics
A61B 5/022
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
021Measuring pressure in heart or blood vessels
022by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
A61B 5/0261
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
026Measuring blood flow
0261using optical means, e.g. infra-red light
Applicants
  • HOCKING, Grant [US]/[US]
Inventors
  • HOCKING, Grant
Agents
  • LISCHER, Dale
Priority Data
62/793,59417.01.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) A METHOD TO QUANTIFY THE HEMODYNAMIC AND VASCULAR PROPERTIES IN VIVO FROM ARTERIAL WAVEFORM MEASUREMENTS
(FR) PROCÉDÉ POUR QUANTIFIER LES PROPRIÉTÉS HÉMODYNAMIQUES ET VASCULAIRES IN VIVO À PARTIR DE MESURES DE FORME D'ONDE ARTÉRIELLE
Abstract
(EN)
Disclosed herein are in vivo non-invasive methods and devices for the measurement of the hemodynamic parameters and aortic valve conformance and compliance in a subject. The method requires measuring the peripheral pulse volume waveform (PVW), the peripheral pulse pressure waveform (PPW), and the peripheral pulse velocity waveform (PUW) from the same artery using a non-invasive device. The waveforms PPW and PUW are used to calculate the waveform dPdU which is used to determine aortic valve ejection volume, closure volume, and quality factor, as well as stroke volume and cardiac output. The disclosed methods and devices are useful in the diagnosis and treatment of aortic valve disease, disorders, and dysfunction.
(FR)
L'invention concerne des procédés et des dispositifs non invasifs in vivo pour la mesure des paramètres hémodynamiques et la conformité de valve aortique chez un sujet. Le procédé nécessite la mesure de la forme d'onde de volume de pulsation périphérique (PVW), de la forme d'onde de pression de pulsation périphérique (PPW) et de la forme d'onde de vitesse de pulsation périphérique (PUW) à partir de la même artère à l'aide d'un dispositif non invasif. Les formes d'onde PPW et PUW sont utilisées pour calculer la forme d'onde dPdU qui est utilisée pour déterminer le volume d'éjection de la valve aortique, le volume de fermeture et le facteur de qualité, ainsi que le volume systolique et la sortie cardiaque. Les procédés et dispositifs de l'invention sont utiles dans le diagnostic et le traitement d'une maladie, de troubles et d'un dysfonctionnement de la valve aortique.
Also published as
Latest bibliographic data on file with the International Bureau