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1. WO2020142789 - NONINVASIVE DETERMINATION OF RESTING STATE DIASTOLE HEMODYNAMIC INFORMATION

Publication Number WO/2020/142789
Publication Date 09.07.2020
International Application No. PCT/US2020/012435
International Filing Date 06.01.2020
IPC
A61B 5/02 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
02Measuring pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography; Heart catheters for measuring blood pressure
CPC
A61B 2560/0223
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2560Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
02Operational features
0223of calibration, e.g. protocols for calibrating sensors
A61B 2576/023
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
2576Medical imaging apparatus involving image processing or analysis
02specially adapted for a particular organ or body part
023for the heart
A61B 5/02028
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
02028Determining haemodynamic parameters not otherwise provided for, e.g. cardiac contractility or left ventricular ejection fraction
A61B 5/022
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
021Measuring pressure in heart or blood vessels
022by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
A61B 5/026
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
026Measuring blood flow
A61B 5/055
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes
05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
055involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
Applicants
  • COVANOS, INC. [US]/[US]
Inventors
  • GIDDENS, Don P.
  • LEFIEUX, Adrien
  • MOLONY, David
  • VENEZIANI, Alessandro
  • VIGUERIE, Alexander
  • SAMADY, Habib
  • LEE, Joo Myung
Agents
  • DYKEMAN, David J.
  • GIROUX, Jonathan
Priority Data
62/788,91406.01.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) NONINVASIVE DETERMINATION OF RESTING STATE DIASTOLE HEMODYNAMIC INFORMATION
(FR) DÉTERMINATION NON INVASIVE D’INFORMATIONS HÉMODYNAMIQUES DE DIASTOLE À L’ÉTAT DE REPOS
Abstract
(EN)
A diastole-based hemodynamic index, such as instantaneous wave-free ratio (IWFR), may be calculated noninvasively for a patient by receiving image data respective of an anatomical region of the patient, creating an electronic model of the anatomical region, creating one or more boundary conditions model value sets representative of flow conditions during diastole, calculating one or more pressure drops at a location in the anatomical region, and determining, based on the calculated pressure drop(s) and based on a reference pressure, a hemodynamic index value, such as IWFR, for the location.
(FR)
La présente invention concerne un indice hémodynamique basé sur la diastole, tel qu’un rapport sans onde instantanée (IWFR), pouvant être calculé de manière non invasive pour un patient en recevant les données d’image respectives d’une région anatomique du patient, en créant un modèle électronique de la région anatomique, en créant un ou plusieurs ensembles de valeurs modèles des conditions limites représentatifs des conditions d’écoulement durant la diastole, en calculant une ou plusieurs chutes de pression à une localisation dans la région anatomique, et en déterminant, sur la base de·des chute·s de pression calculée·s et sur la base d'une pression de référence, une valeur d’indice hémodynamique, telle que l’IWFR, pour la localisation.
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