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1. WO2020142768 - STORING TEMPORAL DATA INTO DNA

Publication Number WO/2020/142768
Publication Date 09.07.2020
International Application No. PCT/US2020/012358
International Filing Date 06.01.2020
IPC
C12Q 1/68 2018.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/68
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
Applicants
  • NORTHWESTERN UNIVERSITY [US]/[US]
  • THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA [US]/[US]
  • THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK [US]/[US]
Inventors
  • TYO, Keith E.J.
  • BHAN, Namita
  • KORDING, Konrad
  • GLASER, Joshua
  • STRUTZ, Jonathan
  • CASTINADO, Alec
Agents
  • MAEBIUS, Stephen
  • AGARWAL, Pavan K.
  • BECK, George
  • BERKOWITZ, Benjamin
  • BRINCKERHOFF, Courtenay C.
  • KAMINSKI, Michael D.
  • LAW, Glenn
  • RAWLINS, Andrew E.
  • SCHORR, Kristel
  • SIMKIN, Michele
Priority Data
62/788,61404.01.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) STORING TEMPORAL DATA INTO DNA
(FR) STOCKAGE DE DONNÉES TEMPORELLES DANS DE L'ADN
Abstract
(EN)
Provided herein are systems and methods for using DNA polymerases to record information onto DNA for single cell high time-resolution recording and for high density data storage. The technology provides a DNA polymerase-based nano scale device that can be genetically encoded to record temporal information about the polymerase's environment into an extending single strand of DNA.
(FR)
L'invention concerne des systèmes et des procédés d'utilisation de polymérases d'ADN pour enregistrer des informations sur de l'ADN pour un enregistrement à haute résolution temporelle à cellule unique et pour un stockage de données à haute densité. La technologie fournit un dispositif de nano-échelle à base d'ADN polymérase pouvant être génétiquement codé pour enregistrer des informations temporelles concernant l'environnement de la polymérase dans un simple brin d'ADN s'étendant.
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