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1. WO2020142644 - METHOD FOR TREATING DRUG OR ALCOHOL DEPENDENCY

Publication Number WO/2020/142644
Publication Date 09.07.2020
International Application No. PCT/US2020/012107
International Filing Date 03.01.2020
IPC
A61K 31/485 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
485Morphinan derivatives, e.g. morphine, codeine
A61P 25/36 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
30for treating abuse or dependence
36Opioid-abuse
C07D 403/02 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/167
02containing two hetero rings
CPC
A61K 31/485
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
47Quinolines; Isoquinolines
485Morphinan derivatives, e.g. morphine, codeine
A61P 25/36
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
30for treating abuse or dependence
36Opioid-abuse
C07D 491/107
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
491Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
02in which the condensed system contains two hetero rings
10Spiro-condensed systems
107with only one oxygen atom as ring hetero atom in the oxygen-containing ring
Applicants
  • AETHER THERAPEUTICS INC. [US]/[US]
Inventors
  • WOLFGANG, Sadee
Agents
  • MEGERDITCHIAN, Samuel, H.
Priority Data
62/788,16704.01.2019US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) METHOD FOR TREATING DRUG OR ALCOHOL DEPENDENCY
(FR) PROCÉDÉ DE TRAITEMENT DE LA DÉPENDANCE AUX MÉDICAMENTS OU À L'ALCOOL
Abstract
(EN)
Provided herein is a method for weaning a subject suffering from a drug addiction or addictive behaviors involving opioid signaling by sequentially blocking peripheral and CNS opioid receptors and modulating opioid dependence.
(FR)
La présente invention concerne un procédé de sevrage d'un sujet souffrant d'une dépendance aux médicaments ou de comportements addictifs impliquant une signalisation opioïde par blocage séquentiel des récepteurs opioïdes périphériques et du SNC et par modulation de la dépendance aux opioïdes.
Also published as
EP2020736176
Latest bibliographic data on file with the International Bureau