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1. WO2020141973 - MIXED BINDING DOMAINS

Publication Number WO/2020/141973
Publication Date 09.07.2020
International Application No. PCT/NL2019/050877
International Filing Date 27.12.2019
IPC
C07K 16/00 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
C07K 16/18 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
C07K 16/46 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
C07K 16/005
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
005constructed by phage libraries
C07K 16/18
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
C07K 16/461
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
461Igs containing Ig-regions, -domains or -residues form different species
C07K 16/468
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
46Hybrid immunoglobulins
468Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
C07K 2317/10
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
10characterized by their source of isolation or production
Applicants
  • MERUS N.V. [NL]/[NL]
Inventors
  • DE KRUIF, Cornelis Adriaan
Agents
  • WITMANS, H. A.
Priority Data
18215995.431.12.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MIXED BINDING DOMAINS
(FR) DOMAINES DE LIAISON MIXTES
Abstract
(EN)
A binding domain or a multimer or a variant thereof which comprises a variable region encoded by a nucleic acid based on, derived or obtained from an animal phylogenetically distal from a human, which variable region is paired with a human variable region.
(FR)
L'invention concerne un domaine de liaison ou un multimère ou un variant de celui-ci qui comprend une région variable codée par un acide nucléique basé sur, dérivé ou obtenu d'un animal phylogénétiquement distal de l'être humain, ladite région variable étant associée à une région variable humaine.
Also published as
EA202191448
IL284353
Latest bibliographic data on file with the International Bureau