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1. WO2020141648 - NOVEL GLIA-LIKE CELLS DIFFERENTIATED FROM SOMATIC CELLS, PREPARATION METHOD THEREFOR, COCKTAIL COMPOSITION FOR PREPARING SAME, CELL THERAPEUTIC AGENT FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME, AND METHOD FOR PREVENTING AND TREATING NEUROLOGICAL DISORDERS BY ADMINISTERING SAME

Publication Number WO/2020/141648
Publication Date 09.07.2020
International Application No. PCT/KR2019/000705
International Filing Date 17.01.2019
IPC
C12N 5/079 2010.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
5Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
07Animal cells or tissues
071Vertebrate cells or tissues, e.g. human cells or tissues
079Neural cells
A61K 35/30 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
A61P 25/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
CPC
A61K 35/30
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
30Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
A61P 25/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
Applicants
  • 주식회사 셀라퓨틱스바이오 CELLAPEUTICS BIO [KR]/[KR]
Inventors
  • 김경규 KIM, Kyeong-Kyu
  • 데데보죠티 DE, Debojyoti
Agents
  • 한양특허법인 HANYANG PATENT FIRM
Priority Data
10-2019-000046502.01.2019KR
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) NOVEL GLIA-LIKE CELLS DIFFERENTIATED FROM SOMATIC CELLS, PREPARATION METHOD THEREFOR, COCKTAIL COMPOSITION FOR PREPARING SAME, CELL THERAPEUTIC AGENT FOR PREVENTING OR TREATING NEUROLOGICAL DISORDERS, COMPRISING SAME, AND METHOD FOR PREVENTING AND TREATING NEUROLOGICAL DISORDERS BY ADMINISTERING SAME
(FR) NOUVELLES CELLULES DU TYPE GLIE DIFFÉRENCIÉES À PARTIR DE CELLULES SOMATIQUES, LEUR PROCÉDÉ DE PRÉPARATION, COMPOSITION COCKTAIL POUR LEUR PRÉPARATION, AGENT THÉRAPEUTIQUE CELLULAIRE POUR LA PRÉVENTION OU LE TRAITEMENT DE TROUBLES NEUROLOGIQUES LES COMPRENANT, ET PROCÉDÉ DE PRÉVENTION ET DE TRAITEMENT DE TROUBLES NEUROLOGIQUES IMPLIQUANT LEUR ADMINISTRATION
(KO) 체세포로부터 분화된 신규한 유사신경교세포, 이의 제조 방법, 이의 제조용 칵테일 조성물, 이를 포함하는 신경 질환 예방 또는 치료용 세포 치료제 및 이를 투여하여 신경 질환을 예방 및 치료하는 방법
Abstract
(EN)
The present invention relates to: novel glia-like cells which are differentiated from somatic cells and of which the amount of HGF secretion is greater than or equal to 20,000 pg/ml; a cocktail composition for preparing same; a preparation method therefor; a cell therapeutic agent for treating neurological disorders, comprising same; and a method for preventing and treating neurological disorders by administering same.
(FR)
La présente invention concerne de nouvelles cellules du type glie étant différenciées à partir de cellules somatiques et dont la quantité de sécrétion de HGF est supérieure ou égale à 20 000 pg/ml; une composition cocktail pour leur préparation; un procédé de préparation correspondant; un agent thérapeutique cellulaire pour traiter des troubles neurologiques, les comprenant; et un procédé pour prévenir et traiter des troubles neurologiques impliquant leur administration.
(KO)
본발명은 HGF분비량 20, 000pg/ml 이상을 포함하는, 체세포로부터 분화된 신규한 유사신경교세포, 이의 제조용 화합물 칵테일 조성물, 이의 제조 방법, 이를 포함하는 신경 질환 치료용 세포 치료제 및 이를 투여하여 신경질환을 예방 및 치료하는 방법에 관한 것이다.
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