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1. WO2020141546 - SYNERGISTIC NUTRITIONAL COMPOSITIONS FOR PAIN MANAGEMENT

Publication Number WO/2020/141546
Publication Date 09.07.2020
International Application No. PCT/IN2019/050963
International Filing Date 30.12.2019
IPC
A23L 33/105 2016.1
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A61K 31/164 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
164of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 36/73 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
A61P 25/02 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
02for peripheral neuropathies
CPC
A23L 33/105
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A61K 31/164
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
16Amides, e.g. hydroxamic acids
164of a carboxylic acid with an aminoalcohol, e.g. ceramides
A61K 36/21
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
21Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
A61K 9/0053
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0053Mouth and digestive tract, i.e. intraoral and peroral administration
A61P 25/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
25Drugs for disorders of the nervous system
02for peripheral neuropathies
Applicants
  • CELAGENEX RESEARCH (INDIA) PVT. LTD. [IN]/[IN]
Inventors
  • DHAMANE, Dhiraj
  • T., Rajendra Prasad
Agents
  • SINGH, Manisha
Priority Data
20192100009202.01.2019IN
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SYNERGISTIC NUTRITIONAL COMPOSITIONS FOR PAIN MANAGEMENT
(FR) COMPOSITIONS NUTRITIONNELLES SYNERGIQUES POUR LA GESTION DE LA DOULEUR
Abstract
(EN)
The present invention discloses a synergistic nutritional composition(s) for pain management. Particularly, the invention relates to synergistic nutritional composition comprising specific combination of palmitoylethanolamide (PEA) and standardized red spinach extract enriched with nitrate content, present in the ratio of 1:0.1 to 1:5 along with pharmaceutically acceptable carriers /excipients. More particularly the invention discloses synergistic nutritional composition comprising combination of PEA and nitrate of the red spinach extract, which are present in the ratio of 1: 0.01 to 1: 0.5. Further the instant synergistic composition is useful for treating neuropathic pain, particularly in the treatment of subject suffering with diabetic peripheral neuropathy and/or small fiber neuropathy.
(FR)
La présente invention concerne une/des composition-s nutritionnelles- synergique-s pour la gestion de la douleur. L'invention concerne, en particulier, une composition nutritionnelle synergique comprenant une combinaison spécifique de palmitoyléthanolamide (PEA) et d'extrait d'épinard rouge standardisé enrichi d'une certaine teneur en nitrate, présent dans le rapport de 1 : 0,1 à 1 : 5 conjointement avec des vecteurs/excipients pharmaceutiquement acceptables. L'invention concerne, plus précisément, une composition nutritionnelle synergique comprenant une combinaison de PEA et de nitrate de l'extrait d'épinard rouge, qui sont présents dans le rapport de 1 : 0,01 à 1 : 0,5. En outre, la composition synergique instantanée s'avère utile pour traiter une douleur neuropathique, en particulier dans le traitement d'un sujet souffrant de neuropathie périphérique diabétique et/ou de neuropathie des petites fibres.
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