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1. WO2020141180 - LIQUID NICOTINE FORMULATION

Publication Number WO/2020/141180
Publication Date 09.07.2020
International Application No. PCT/EP2019/087198
International Filing Date 31.12.2019
Chapter 2 Demand Filed 30.10.2020
IPC
A24B 15/16 2020.1
AHUMAN NECESSITIES
24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
15Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
10Chemical features of tobacco products or tobacco substitutes
16of tobacco substitutes
A24F 47/00 2020.1
AHUMAN NECESSITIES
24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
FSMOKERS’ REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
47Smokers’ requisites not otherwise provided for
A24B 15/28 2006.1
AHUMAN NECESSITIES
24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
15Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
18Treatment of tobacco products or tobacco substitutes
28by chemical substances
CPC
A24B 15/167
AHUMAN NECESSITIES
24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
15Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
10Chemical features of tobacco products or tobacco substitutes
16of tobacco substitutes
167in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
A24B 15/28
AHUMAN NECESSITIES
24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
15Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
18Treatment of tobacco products or tobacco substitutes
28by chemical substances
A61K 31/465
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
435having six-membered rings with one nitrogen as the only ring hetero atom
465Nicotine; Derivatives thereof
A61K 9/12
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
10Dispersions; Emulsions
12Aerosols; Foams
Applicants
  • PHILIP MORRIS PRODUCTS S.A. [CH]/[CH]
Inventors
  • SCHALLER, Jean-Pierre
  • VUARNOZ-BIZE, Aline
Agents
  • MILLBURN, Julie
Priority Data
18215964.031.12.2018EP
18215966.531.12.2018EP
18215969.931.12.2018EP
18215976.431.12.2018EP
18215983.031.12.2018EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) LIQUID NICOTINE FORMULATION
(FR) FORMULATION DE NICOTINE LIQUIDE
Abstract
(EN)
A liquid nicotine formulation for use in an aerosol-generating system, the liquid nicotine formulation comprising one or more water-miscible solvents, one or more water-immiscible solvents having a water solubility at 20°C of less than or equal to about 100 mg/ml and one or more water-soluble organic acids, wherein the liquid nicotine formulation has a water-immiscible solvent content of greater than or equal to about 2 percent by weight. A liquid nicotine formulation for use in an aerosol-generating system, the liquid nicotine formulation comprising one or more water-miscible solvents, one or more water-immiscible solvents having a partition coefficient (log P) at 20°C of greater than or equal to about 0.05, and one or more water-soluble organic acids, wherein the liquid nicotine formulation has a water-immiscible solvent content of greater than or equal to about 2 percent by weight. A cartridge for use in an aerosol-generating system, the cartridge containing the liquid nicotine formulation. An aerosol-generating system comprising the liquid nicotine formulation and an atomiser configured to generate an aerosol from the liquid nicotine formulation.
(FR)
L'invention concerne une formulation de nicotine liquide destinée à être utilisée dans un système de génération d'aérosol, cette formulation de nicotine liquide comprenant un ou plusieurs solvants miscibles à l'eau, un ou plusieurs solvants non miscibles à l'eau ayant une solubilité dans l'eau à 20 °C inférieure ou égale à environ 100 mg/ml et un ou plusieurs acides organiques solubles dans l'eau, la teneur en solvants non miscibles à l'eau de la formulation de nicotine liquide étant supérieure ou égale à environ 2 pour cent en poids. L'invention concerne une formulation de nicotine liquide destinée à être utilisée dans un système de génération d'aérosol, cette formulation de nicotine liquide comprenant un ou plusieurs solvants miscibles à l'eau, un ou plusieurs solvants non miscibles à l'eau ayant un coefficient de partage (log P) à 20 °C supérieur ou égal à environ 0,05, et un ou plusieurs acides organiques solubles dans l'eau, la teneur en solvants non miscibles à l'eau de la formulation de nicotine liquide étant supérieure ou égale à environ 2 pour cent en poids. L'invention concerne également une cartouche destinée à être utilisée dans un système de génération d'aérosol, cette cartouche contenant ladite formulation liquide de nicotine. L'invention concerne par ailleurs un système de génération d'aérosol comprenant cette formulation de nicotine liquide et un atomiseur conçu pour générer un aérosol à partir de ladite formulation de nicotine liquide.
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