Processing

Please wait...

Settings

Settings

Goto Application

1. WO2020139962 - HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTIN AND GALECTIN-3

Publication Number WO/2020/139962
Publication Date 02.07.2020
International Application No. PCT/US2019/068600
International Filing Date 26.12.2019
IPC
C07H 19/04 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen as ring hetero atom
A61K 31/7056 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
7042Compounds having saccharide radicals and heterocyclic rings
7052having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
7056containing five-membered rings with nitrogen as a ring hetero atom
A61P 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
C07H 19/04
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
19Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides ; Anhydro-derivatives thereof
02sharing nitrogen
04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
Applicants
  • GLYCOMIMETICS, INC. [US]/[US]
Inventors
  • MAGNANI, John L.
  • PETERSON, John M.
  • SARKAR, Arun K.
  • VOHRA, Yusufbhai U.
  • GHOSH, Indranath
  • NOGUEIRA, Jason
Agents
  • WEINGARTEN, M., David
  • O'QUINN, Ryan P.
  • MACALPINE, Jill K.
Priority Data
62/785,56527.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) HETEROBIFUNCTIONAL INHIBITORS OF E-SELECTIN AND GALECTIN-3
(FR) INHIBITEURS HÉTÉROBIFONCTIONNELS D'E-SÉLECTINE ET DE GALECTINE-3
Abstract
(EN)
Compounds, compositions, and methods for treatment and/or prevention of at least one disease, disorder, and/or condition by inhibiting binding of an E-selectin, galectin-3, or E-selectin and galectin-3 to ligands are disclosed. For example, heterobifunctional inhibitors of E-selectin and galectin-3 are described and pharmaceutical compositions comprising at least one such agent is described.
(FR)
L'invention concerne des composés, des compositions et des procédés pour le traitement et/ou la prévention d'au moins une maladie, un trouble et/ou un état par inhibition de la liaison d'une E-sélectine, de la galectine-3 ou d'E-sélectine et de galectine-3 à des ligands. Par exemple, l'invention concerne des inhibiteurs hétérobifonctionnels d'E-sélectine et de galectine-3 et des compositions pharmaceutiques comprenant au moins un tel agent.
Latest bibliographic data on file with the International Bureau