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1. WO2020139926 - ANTI-CTLA4 ANTIBODIES AND METHODS OF USE THEREOF

Publication Number WO/2020/139926
Publication Date 02.07.2020
International Application No. PCT/US2019/068548
International Filing Date 26.12.2019
IPC
C07K 16/28 2006.1
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins, e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
A61P 35/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
CPC
A61K 2039/505
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
505comprising antibodies
A61P 35/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
35Antineoplastic agents
C07K 14/70521
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
14Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435from animals; from humans
705Receptors; Cell surface antigens; Cell surface determinants
70503Immunoglobulin superfamily
70521CD28, CD152
C07K 16/2818
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
16Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
18against material from animals or humans
28against receptors, cell surface antigens or cell surface determinants
2803against the immunoglobulin superfamily
2818against CD28 or CD152
C07K 2317/24
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
20characterized by taxonomic origin
24containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
C07K 2317/52
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
KPEPTIDES
2317Immunoglobulins specific features
50characterized by immunoglobulin fragments
52Constant or Fc region; Isotype
Applicants
  • XILIO DEVELOPMENT, INC. [US]/[US]
Inventors
  • KAROW, Margaret
Agents
  • CHEN, Fangli
Priority Data
62/785,11126.12.2018US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) ANTI-CTLA4 ANTIBODIES AND METHODS OF USE THEREOF
(FR) ANTICORPS ANTI-CTLA4 ET LEURS MÉTHODES D'UTILISATION
Abstract
(EN)
The invention provides anti-CTLA4 binding proteins (e.g., antibodies, bispecific antibodies, and chimeric receptors) and their use in treating and preventing cancer, as well as compositions and kits comprising the anti-CTLA4 binding proteins.
(FR)
L'invention concerne des protéines de liaison anti-CTLA4 (par exemple, des anticorps, des anticorps bispécifiques et des récepteurs chimériques) et leur utilisation dans le traitement et la prévention du cancer, ainsi que des compositions et des kits comprenant les protéines de liaison anti-CTLA4.
Also published as
IL284381
IL284382
SA521422395
SA521422415
Latest bibliographic data on file with the International Bureau