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1. WO2020139311 - "ECOPRIMAVAC" ESCERICHIA- AND ENTEROCOCCUS-BASED INACTIVATED LIQUID VACCINE AGAINST E. COLI AND ENTEROCOCCI, METHOD FOR PRODUCTION THEREOF, AND METHOD OF TREATMENT AND PROPHYLAXIS USING SAME

Publication Number WO/2020/139311
Publication Date 02.07.2020
International Application No. PCT/UA2019/000165
International Filing Date 27.12.2019
Chapter 2 Demand Filed 15.10.2020
IPC
A61K 35/74 2015.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
A61K 39/108 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
108Escherichia; Klebsiella
A61K 39/07 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
07Bacillus
A61K 39/116 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
116Polyvalent bacterial antigens
A61P 31/04 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
CPC
A61K 35/74
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
35Medicinal preparations containing materials or reaction products thereof with undetermined constitution
66Microorganisms or materials therefrom
74Bacteria
A61K 39/07
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
07Bacillus
A61K 39/116
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39Medicinal preparations containing antigens or antibodies
02Bacterial antigens
116Polyvalent bacterial antigens
A61P 31/04
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
31Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
04Antibacterial agents
Applicants
  • МАРКОВ, Игорь Семёнович MARKOV, Ihor Semenovych [UA]/[UA]
Inventors
  • МАРКОВ, Игорь Семёнович MARKOV, Ihor Semenovych
  • МАРКОВ, Артём Игоревич MARKOV, Artem Ihorovych
Agents
  • ЛЕСНАЯ, Татьяна Леонидовна LISNA, Tetiana Leonidivna
Priority Data
a 2018 1297727.12.2018UA
Publication Language Russian (RU)
Filing Language Russian (RU)
Designated States
Title
(EN) "ECOPRIMAVAC" ESCERICHIA- AND ENTEROCOCCUS-BASED INACTIVATED LIQUID VACCINE AGAINST E. COLI AND ENTEROCOCCI, METHOD FOR PRODUCTION THEREOF, AND METHOD OF TREATMENT AND PROPHYLAXIS USING SAME
(FR) VACCIN LIQUIDE INACTIVÉ CONTRE L'ECHÉRICHIA-ENTÉROCOQUE "ECOPRIMAVAK" CONTRE LES BACILLES INTESTINAUX ET LES ENTÉROCOQUES, PROCÉDÉ DE PRODUCTION, PROCÉDÉ DE TRAITEMENT ET PRÉVENTION À L'AIDE DE CELUI-CI
(RU) ЕШЕРИХИОЗНО-ЭНТЕРОКОККОВАЯ ИНАКТИВИРОВАННАЯ ЖИДКАЯ ВАКЦИНА «ЕКОПРИМАВАК» ПРОТИВ КИШЕЧНОЙ ПАЛОЧКИ И ЭНТЕРОКОККОВ, СПОСОБ ЕЕ ИЗГОТОВЛЕНИЯ, СПОСОБ ЛЕЧЕНИЯ И ПРОФИЛАКТИКИ ЕЮ
Abstract
(EN)
The group of inventions relates to medical microbiology and the pharmaceutical industry, and more particularly to vaccine preparations, and even more particularly to vaccines against intestinal enterobacteriaceae and enterococci, methods for production thereof and methods of treatment and prophylaxis of localised and systemic, acute and chronic diseases of bacterial aetiology in children and adults. The EcoPrimavac Escerichia- and Enterococcus-based inactivated liquid vaccine against E. coli and Enterococcus comprises Escherichia coli, Enterococcus faecalis, Enterococcus faecium and Enterococcus durans bacterial strains, with no less than 22 bacterial strains in total, and more particularly: Escherichia coli - 9, Enterococcus faecalis - 8, Enterococcus faecium - 3, Enterococcus durans - 2 from specific locations, isolated from various acute and chronic inflammatory diseases of bacterial aetiology in children and adults, which have various degrees of antibiotic resistance and include hospital strains having 100% antibiotic resistance, inter alia, bacterial strains deposited at the Depository of the Institute of Microbiology and Virology of the National Academy of Sciences of Ukraine.
(FR)
Ce groupe d'inventions se rapporte au domaine de la microbiologie médicale, de l'industrie pharmaceutique, et concerne notamment des préparations de vaccins et plus particulièrement des vaccins contre les entobactéries intestinales et les entérocoques, ainsi que des procédés de production et des procédés de traitement et de prévention, et peut être utilisée afin de traiter et de prévenir des affections locales et systémiques, aiguës et chroniques d'éthiologie bactérienne chez des enfants et des adultes. L'invention concerne un vaccin liquide contre l'echérichia-enérocoque inactivé contre les bacilles intestinaux et les entérocoques "EcoPrimavak" qui comprend des souches de bactéries Escherichia coli, Enterococcus faecalis, Enterococcus faecium et Enterococcus durans, soit au total au moins 22 souches de bactéries et notamment: Escherichia coli - 9, Enterococcus faecalis - 8, Enterococcus faecium - 3, Enterococcus durans - 2 à un emplacement déterminé, qui sont destinées à diverses affections inflammatoires aiguës et chroniques d'éthiologie bactérienne chez les enfants et les adultes, avec divers taux de résistance aux antibiotiques, y compris des souches hospitalières ayant une résistance de 100% aux antibiotiques, et y compris des souches de bactéries déposées dans le Dépositoire de l'Institut de microbiologie et de virologie de l'Académie nationale des sciences d'Ukraine.
(RU)
Группа изобретений относится к медицинской микробиологии, фармацевтической промышленности, в частности к вакцинным препаратам, а именно, к вакцинам против кишечных энтеробактерий и энтерококкам, способам их изготовления и способам лечения и профилактики, и может быть использована для лечения и профилактики локальных и системных, острых и хронических заболеваний бактериальной этиологии у детей и взрослых. При этом эшерихиозно- энтерококковая инактивированная жидкая вакцина против кишечной палочки и энтерококка ЕкоПримавак включает штаммы бактерий Escherichia coli, Enterococcus faecalis, Enterococcus faecium и Enterococcus durans, всего не менее 22-х штаммов бактерий, а именно: Escherichia coli - 9, Enterococcus faecalis - 8, Enterococcus faecium - 3, Enterococcus durans - 2 определенной локации, выделенных при различных острых и хронических воспалительных заболеваниях бактериальной этиологии у детей и взрослых, с разной степенью резистентности к антибиотикам, включая госпитальные штаммы со 100%-ной антибиотикорезистентностью, в том числе штаммы бактерий, депонированные в Депозитарии Института микробиологии и вирусологии Национальной академии наук Украины.
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